Results 71 to 80 of about 32,707,685 (254)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
National Center for Environmental Health brochure
CDC\u2019s National Center for Environmental Health (NCEH) plans, directs, and coordinates a national program to maintain and improve the health of the American people.
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Annual report 2018 - National Women and Infants Health Programme
, 2019 In 2016, a robust policy and strategic framework for the development and delivery of maternity services was established in Ireland with the launch of the National Maternity Strategy – Creating a Better Future Together, 2016-2026 in January 2016, the ...
National Women and Infants Health Programme
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Health sector decentralization and Indonesia ' s nutrition programs : opportunities and challenges [PDF]
This policy concept paper is intended to assist the center in navigating the tension between opportunities and challenges as activities are adapted to the decentralized national nutrition policy, and to help guide districts and provinces in the conduct o
Choi, Yoonjoung +4 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Gateway National Recreation Area program guide.
Description based on: Vol. 1, no. 3 (fall/winter 1990); title from caption.Mode of access: Internet.Split into: Gateway National Recreation Area (Agency : U.S.). Jamaica Bay Unit.
Gateway National Recreation Area (Agency : U.S.)
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source