Results 21 to 30 of about 1,618,479 (311)

Estrogen-related receptor γ causes osteoarthritis by upregulating extracellular matrix-degrading enzymes

open access: yesNature Communications, 2017
The pathogenesis of osteoarthritis is unclear. The authors show that estrogen-related receptor gamma is upregulated in cartilage from patients and mouse models, where it drives production of matrix-degrading MMPs in chondrocytes, and that its ...
Young-Ok Son   +10 more
doaj   +1 more source

Newer initiatives under national tuberculosis elimination programme [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2023
National Tuberculosis Elimination Programme (NTEP) is a Centrally Sponsored Scheme being implemented under the aegis of the National Health Mission with resource sharing between the State Governments and the Central Government.
Anugraha John   +3 more
doaj  

Public health initiatives and Ayush: Projects to policy

open access: yesInternational Journal of Ayurveda Research, 2023
Public health is engrossed and a rootstock in Ayurveda and classical literature reflects public health care at every turn. Ayush-public health initiative (PHI) is an all-inclusive approach toward health care and wellness. Starting in 2007–08 as a part of
Prashant Kumar Gupta   +4 more
doaj   +1 more source

Reframing dementia care in Maltese Hospitals [PDF]

open access: yes, 2016
This commentary addresses the urgent need to improve the care of patients with dementia and cognitive impairment in Maltese hospitals by proposing a number of dementia-friendly hospital-based initiatives.
Scerri, Anthony, Scerri, Charles
core   +1 more source

N-α-acetyltransferase 10 (NAA10) in development: the role of NAA10

open access: yesExperimental and Molecular Medicine, 2018
Developmental disorders: Focus on enzyme activity Further investigations are needed into the role of a key enzyme in biological development and its encoding gene.
Mi-Ni Lee, Hyae Yon Kweon, Goo Taeg Oh
doaj   +1 more source

RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family

open access: yesNature Communications, 2019
Osteoarthritis is characterised by degeneration of joint cartilage. Here the authors show that the RNA-binding protein ZFP36L1 is upregulated in chondrocytes of humans and mice with osteoarthritis, and that its knockdown in mouse joints protects ...
Young-Ok Son   +4 more
doaj   +1 more source

CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs

open access: yesCell Reports, 2020
Summary: CD137, a potent costimulatory receptor for CD8+ T cells, is expressed in various non-T cells, but little is known about its regulatory functions in these cells. In this study, we show that CD137 signaling, specifically in intestinal CD11b−CD103+
Jing Jin   +16 more
doaj   +1 more source

Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation

open access: yesNature Communications, 2017
VLDLR regulates cellular lipoprotein uptake and storage. Here, the authors show that VLDLR, expressed on adipose tissue macrophages, is upregulated in obesity and promotes adipose tissue inflammation by upregulating ceramide production and facilitating ...
Kyung Cheul Shin   +10 more
doaj   +1 more source

The Need for Revised Resolution Regimes and Supervisory Arrangements [PDF]

open access: yes, 2011
In October 2010, having drawn crucial lessons fom the Financial Crisis which was triggered in 2007, and whose impact was still evident at the time, the Financial Stability Board Recommendations on systemically important financial institutions „called ...
Ojo, Mariane.B.
core   +2 more sources

What promotes greater use of the corporate bond market? A study of the issuance behaviour of firms in Asia [PDF]

open access: yes, 2014
This paper investigates bond market development in Asia by exploring the determinants of firms' decisions to issue public debt in a range of Asian economies.
ASEAN   +39 more
core   +3 more sources

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