Results 51 to 60 of about 1,627,853 (314)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Ballot initiatives and the national debate on immigration

open access: yesTransatlantica, 2012
Proposition 187 voted by Californians in 1994 was the first in a long series of ballot initiatives proposed by other states limiting access to welfare programs and education to illegal immigrants.
Mario Menéndez
doaj   +1 more source

Meeting the Challenge: Opportunities for Midwest Action on Climate Change [PDF]

open access: yes, 2007
Examines how climate change efforts in the Midwest could complement coastal initiatives to bring about more meaningful national action.
Adele Simmons, Julia Parzen
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Digital and Media Literacy: A Plan of Action [PDF]

open access: yes, 2010
Outlines a community education movement to implement Knight's 2009 recommendation to enhance digital and media literacy. Suggests local, regional, state, and national initiatives such as teacher education and parent outreach and discusses ...
Renee Hobbs
core  

National Income, Strategic Discontinuity, and Converging Trajectories of Macroeconomic Policy Initiatives: An Empirical Study of China [PDF]

open access: yes, 2018
The framework of converging trajectories of macroeconomic policy initiatives is employed in the context of strategic discontinuity to study the national income of an advancing economy.
Li, Hsi C.   +2 more
core   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

School to where? A literature review on economic outcomes of youth with Disabilities [PDF]

open access: yes, 2002
This paper summarizes the recent empirical literature on post-secondary school outcomes of youth with disabilities. Our summary illustrates the variation in characteristics and outcomes that exist in several subpopulations generally defined as youth with
Maag, Elaine, Wittenburg , David C.
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Emerging role of the orphan nuclear receptor estrogen-related receptor gamma in liver metabolic diseases

open access: yesLiver Research, 2019
Estrogen-related receptor gamma (ERRγ) is one of three members of the ERR family and remains an orphan, as there are no known natural ligands. ERRγ is an inducible transcription factor, and its ligand-independent transcriptional activity is regulated by ...
Don-Kyu Kim, Hueng-Sik Choi
doaj   +1 more source

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