Results 61 to 70 of about 1,627,853 (314)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Nature CommunicationsLiquid-liquid phase separation (LLPS) facilitates the formation of membraneless organelles within cells, with implications in various biological processes and disease states.
Yong Ryoul Kim +17 more
doaj +1 more source
New National Initiatives of Modernizing Education in China
ECNU Review of Education, 2019 Purpose: This article aims to shed light on a latest education policy blueprint in China, titled China’s education modernization 2035 , which was issued by the Central Government of China in February of 2019.
Yiming Zhu
doaj +1 more source
Evolution of an Epidemic: 25 Years of HIV/AIDS Media Campaigns in the U.S. [PDF]
, 2006 Traces the development of national public education campaigns, from those aimed at raising general awareness, to treatment and prevention. Looks at the role played by entertainment media, including more recent initiatives focusing on the global ...
Julia Davis
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A common heritage: EU environmental law and national judges [PDF]
, 2010 Enforcement of EU environmental law is one of the most prominent challenges in the field of environmental policy. In this respect, national judges have to play a key-role for ensuring that EU environmental law is correctly applied. They have to guarantee
Garcia Burgues, Julio +4 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Intitatives for a Smart Economy 2.0 [PDF]
, 2017 Just like its predecessor, I4SE 2.0 is organized in a manner that focuses on those sectors of the local economy identified by WNYREDC as growth sectors.
Poloncarz, Mark
core +1 more source
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source