Results 41 to 50 of about 2,131,183 (309)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Biogas quality and nutrient remediation in palm oil mill effluent through Chlorella vulgaris cultivation using a photobioreactor [PDF]

Global Journal of Environmental Science and Management
BACKGROUND AND OBJECTIVES: During this energy transition, research is being done to develop sustainable ways to support the shift to a decarbonized energy and production system.
T. Handayani, I.N. Djarot, N. Widyastuti, F.D. Arianti, A. Rifai, A.I. Sitomurni, M.M.A. Nur, R.N. Dewi, N. Nuha, J. Haryanti, D. Pinardi, Y. Suryana, A. Aziz, E. Syamsudin, T. Rochmadi, P.A. Lomak, A. Hadi, M.D. Pertiwi, E. Yuniastuti, N.A. Putri   +19 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

RETRACTED: INNOVATION ACTIVITIES: INDICATORS AND IMPLEMENTATION METHODS

Модернизация, инновация, развитие, 2016
Retracted articleInnovation is a new development in the field of technology, work organization or management that provides for increased efficiency. Today, the innovation process has become nonlinear.
A. L. Gaponenko, S. V. Pirogov, I. F. Chernyavski   +2 more
doaj  

ERAWATCH Country Reports 2013: United Kingdom [PDF]

, 2014
The Analytical Country Reports analyse and assess in a structured manner the evolution of the national policy research and innovation in the perspective of the wider EU strategy and goals, with a particular focus on the performance of the national ...
CUNNINGHAM Paul
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

MACEDONIAN NATIONAL INNOVATION SYSTEM – MAIN CHALLENGES

Economic Review, 2014
It is generally accepted that the National Innovation Systems (NIS) are one of the most comprehensive systemic approaches that give insight into innovative and economic performance of a country.
Radmil Polenakovik, Ivana Stankovska, Bojan R. Jovanovski   +2 more
doaj   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

ERAWATCH Country Reports 2013: Montenegro [PDF]

, 2014
The Analytical Country Reports analyse and assess in a structured manner the evolution of the national policy research and innovation in the perspective of the wider EU strategy and goals, with a particular focus on the performance of the national ...
KALUDJEROVIC Jadranka
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source