Results 51 to 60 of about 606,689 (307)

Cocoa farmers' characteristics on climate variability and its effects on climate change adaptation strategy [PDF]

Global Journal of Environmental Science and Management
BACKGROUND AND OBJECTIVES: Climate change has a greater influence on agriculture through local climate variability than global climate patterns. The impact of climate change on agricultural productivity and shifts in crop patterns varies significantly ...
I. Idawati, N.A. Sasongko, A.D. Santoso, M. Septiani, T. Handayani, A.Y.N. Sakti, B.D. Purnamasari   +6 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

РАЗВИТИЕ ВЫСШЕГО ОБРАЗОВАНИЯ В ФОРМИРОВАНИИ НАЦИОНАЛЬНОЙ ИННОВАЦИОННОЙ СИСТЕМЫ ЭКВАДОРА

Вестник Северо-Кавказского федерального университета, 2022
The Republic of Ecuador has shown significant successes in socio-economic development against the backdrop of several Latin American countries. So, Ecuador is in 123rd place out of 190, which make up the Doing Business rating. In terms of GDP, Ecuador is
T. Kolmykova, V. R. Calderon
doaj  

THE ROLE OF INNOVATION POLICY IN THE NATIONAL INNOVATION SYSTEM: THE CASE OF ESTONIA; pp. 249–272 [PDF]

Trames, 2015
The article highlights the unifying role of innovation policy in shaping and ensuring the functioning of a national innovation system. The first part of the article deals with the need for public sector intervention in innovation processes.
Janno Reiljan, Ingra Paltser
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

National innovation policy in Cyprus

, 2001
This paper analyses the concept of national innovation policy (NIP) and puts forward arguments supporting the need for a NIP for small developing economies like Cyprus.
Dickson, K, Hadjimanolis, A
core   +1 more source

APPROACHES TO EVALUATING INNOVATIVE POTENTIAL OF THE COUNTRY'S ECONOMY

Вестник Северо-Кавказского федерального университета, 2022
Challenges to the sustainable development of countries are intensifying due to globalization processes and constantly growing international competition.
O. Lashkareva, G. Kozhakmetova
doaj  

Directions of Development of National Innovation System

Модернизация, инновация, развитие, 2017
Purpose: to study the feasibility of building a national innovation system on the principles of rational self-sufficiency of the domestic economy. Methods: during research following methods were applied: comparative and correlative analysis, correlations,
Artur D. Bobryshev, Maria V. Chekadanova
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source