Results 121 to 130 of about 27,035,508 (303)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

INTERNATIONAL ORGANIZATIONS ARE CREATED BY STATES TO FURTHER INTEREST BUT THEY HAVE NOW ASSUMED AUTHORITY INDEPENDENT OF THE STATES THAT CREATED THEM: THE ANALYSIS OF PROS AND CONS

open access: yesInternational Studies Journal
International organizations (IOs) are established by sovereign states to promote cooperation, address global challenges, and advance shared interests.
SUNDAY ORINYA, BADAMASI SAIDU
doaj  

A China e seus interesses nacionais

open access: yesMeridiano 47, 2017
O presente artigo tem como tema a evolução histórico-sociológica da China e a configuração de seus interesses nacionais.
Paulo Roberto Almeida
doaj  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Trade and the national interest

open access: yes, 2003
The policy document 'Advancing the National Interest' reveals much about the Howard government's understanding of contemporary economic and geopolitical realities.
Beeson, Mark
core   +1 more source

The National Banking System: empirical observations [PDF]

open access: yes
This paper provides a summary of the main features of U.S. financial and banking data during the period of the National Banking System (1863–1914). The purpose of the paper is to provide an overview of the stylized facts associated with the era, with an ...
Bruce Champ
core  

The Europeanization of Interest Representation: A Strategic Decision-Making Analysis of UK Business and Environmental Interests [PDF]

open access: yes, 2002
The point of departure for this paper is that the European Union (EU) has affected national politics, policies and polities. This process, labelled Europeanization, has led to changes in two interconnected political dimensions.
Fairbrass, Jenny., Fairbrass, Jenny
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

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