Results 101 to 110 of about 4,328,152 (304)

Capital, Interest, and Aggregate Intertemporal Substitution [PDF]

Financial economics research has suggested that expected returns are not the same across assets, and that their movements over time are not simply described or explained.
Casey B. Mulligan
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The Europeanization of Interest Representation: A Strategic Decision-Making Analysis of UK Business and Environmental Interests [PDF]

, 2002
The point of departure for this paper is that the European Union (EU) has affected national politics, policies and polities. This process, labelled Europeanization, has led to changes in two interconnected political dimensions.
Fairbrass, Jenny., Fairbrass, Jenny
core  

Interest Groups and the United Nations (UN)

, 2019
Some of the most exciting controversies about transnational interest group politics revolve around the United Nations (UN), a major incuba- tor of ideas and a hub in global governance.
Dellmuth, Lisa Maria,, Lisa Maria Dellmuth, Dellmuth, Lisa Maria   +2 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A China e seus interesses nacionais

Meridiano 47, 2017
O presente artigo tem como tema a evolução histórico-sociológica da China e a configuração de seus interesses nacionais.
Paulo Roberto Almeida
doaj  

Analysis of Effects of Foreign Bank Entry on Credit Interest Rate Behavior in Serbia [PDF]

Following foreign bank entry, credit interest rates have been extremely high in Serbia compared with a reference group of countries: Croatia, Bulgaria and Romania.
Đorđe Đukić
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

INTERNATIONAL ORGANIZATIONS ARE CREATED BY STATES TO FURTHER INTEREST BUT THEY HAVE NOW ASSUMED AUTHORITY INDEPENDENT OF THE STATES THAT CREATED THEM: THE ANALYSIS OF PROS AND CONS

International Studies Journal
International organizations (IOs) are established by sovereign states to promote cooperation, address global challenges, and advance shared interests.
SUNDAY ORINYA, BADAMASI SAIDU
doaj  

NATIONAL SECURITY AS A LEGAL CATEGORY [PDF]

Challenges of the Knowledge Society, 2019
This article describes such notions as “security”, “national security”, types of national security, recent changes in the National security of Bulgаrian doctrine.
Kremena RAYANOVA
doaj