Results 111 to 120 of about 5,682,095 (261)
Trade, Democracy, and the FTAA: Public Access to the Process of Constructing a Free Trade Area of the Americas [PDF]
The Article concentrates on access for non-profit or public interest elements of civil society rather than for-profit business interests, because public interest organizations have been more marginalized from the FTAA, and their interests are more ...
Dannenmaier, Eric
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
International organizations (IOs) are established by sovereign states to promote cooperation, address global challenges, and advance shared interests.
SUNDAY ORINYA, BADAMASI SAIDU
doaj
A China e seus interesses nacionais
O presente artigo tem como tema a evolução histórico-sociológica da China e a configuração de seus interesses nacionais.
Paulo Roberto Almeida
doaj
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
What if the euro had never been launched? A counterfactual analysis of the macroeconomic impact of euro membership [PDF]
The aim of this paper is to gauge quantitatively the macroeconomic impact of EMU membership. Building on the Global VAR framework designed by Pesaran et al.
Emmanuel Dubois +2 more
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The flaws in Keynsian borrow and spend [PDF]
Borrow and spend is a policy with several weaknesses. 1, it involves government borrowing something, that is money, which government can create in limitless quantities any time.
Musgrave, Ralph S.
core +1 more source
Mapping digital media: digital television, the public interest, and European regulation [PDF]
Discussion of digital television has focused on switch-over dates, set-top boxes and the technical and economic implications of switch-over. This paper, by contrast, focusses on public interest obligations and citizenship values such as freedom, access ...
Iosifidis, P.
core

