Results 111 to 120 of about 27,035,508 (303)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Interest Groups and the United Nations (UN)
, 2019 Some of the most exciting controversies about transnational interest group politics revolve around the United Nations (UN), a major incuba- tor of ideas and a hub in global governance.
Dellmuth, Lisa Maria, +2 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Afrocentrism, national interest and citizen welfare in Nigeria's foreign policy maneuvers. [PDF]
F1000Res, 2020 Mbara GC, Gopal N.
europepmc +1 more source
Budget Deficits, National Saving, and Interest Rates [PDF]
macroeconomics, Budget Deficits, National Saving, Interest ...
Peter R. Orszag, William G. Gale
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
National Security Strategy of the Republic of Poland, 2007
, 2007 This document presents a new approach to Poland's national security strategy, correlated with allied strategies – NATO's Strategic Concept and the European Security Strategy.
Ministry of National Defence of Poland
core
Philosopher's Corner: What is Science in the National Interest?
, 2018 The article addresses whether a list can capture our national interests, whether Congress is especially in touch with our national interests, and whether science needs to be in the national interest in order to justify federal ...
J. Britt Holbrook
core +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Transformational analysis of the national interest
, 2004 This thesis explains the independence of East Timor by investigating the idea of "national interest". It shows how the policymakers' "national interest" calculations were opposed by a transnational solidarity movement.
Clinton Fernandes (13788436)
core +1 more source