Results 41 to 50 of about 1,345,097 (304)
The Impact Of Federal Legislation On Governmental And Special Libraries [PDF]
It has become increasingly obvious that libraries today cannot provide adequate service under conditions of local self-sufficiency. A variety of programs are required on the national level which cannot be provided by individual libraries or ...
Skipper, James E.
core
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
The medical science DMZ: a network design pattern for data-intensive medical science [PDF]
: Objective We describe a detailed solution for maintaining high-capacity, data-intensive network flows (eg, 10, 40, 100 Gbps+) in a scientific, medical context while still adhering to security and privacy laws and regulations. Materials and Methods
Balas, Edward +8 more
core +1 more source
Objective RAId is a software package that has been actively developed for the past 10 years for computationally and visually analyzing MS/MS data. Founded on rigorous statistical methods, RAId’s core program computes accurate E-values for peptides and ...
Brendan Joyce +5 more
doaj +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Background Capturing sentence semantics plays a vital role in a range of text mining applications. Despite continuous efforts on the development of related datasets and models in the general domain, both datasets and models are limited in biomedical and ...
Qingyu Chen +4 more
doaj +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Ranking Medical Subject Headings using a factor graph model. [PDF]
Automatically assigning MeSH (Medical Subject Headings) to articles is an active research topic. Recent work demonstrated the feasibility of improving the existing automated Medical Text Indexer (MTI) system, developed at the National Library of Medicine
Demner-Fushman, Dina +4 more
core
Introduction: Nowadays and with the increasing role of the worldwide web as one of the most important sources of information on the one hand, and the enhancement of its usability on the other, it is necessary for the web designers and developers to be ...
Sedigheh Mohammadesmaeil +1 more
doaj
Semantic annotation of consumer health questions
Background Consumers increasingly use online resources for their health information needs. While current search engines can address these needs to some extent, they generally do not take into account that most health information needs are complex and can
Halil Kilicoglu +6 more
doaj +1 more source

