Results 41 to 50 of about 7,978 (260)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Echoes of the Beatles in Hamburg

open access: yesJournal of Beatles Studies
The Beatles’ Hamburg period is important for the group’s early career in particular, and is among the most rewritten periods, not least after the group split in 1970.
Hans Olof Gottfridsson
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Un accès payant pour des ressources éducatives en licence Creative Commons : un paradoxe étudié au prisme d’une étude de cas, Faq2Sciences

open access: yesInternational Journal of E-learning and Distance Education
Le projet Faq2Sciences porté par l’Université Numérique Thématique Unisciel représente une banque de plusieurs milliers d’exercices en sciences naturelles, mathématiques et informatiques, alimentée par de nombreuses institutions d’enseignement supérieur.
Matthieu Cisel, Nicolas Laudier
doaj   +1 more source

Sparking a debate on coal: Case study on the Indian Government’s crackdown on Greenpeace

open access: yesCosmopolitan Civil Societies: An Interdisciplinary Journal, 2018
Non-governmental organisations working on rights based issues in India have recently been in the firing line of the government. The controversial Foreign Contribution Regulation Act (FCRA), originally instituted during national emergency in 1976, has ...
Ruchira Talukdar
doaj   +1 more source

Recentralization of Regional Authority: Legal Implications of the Enactment of Emergency Law Number 2 of 2022 on Job Creation in Regional Autonomy

open access: yesAs-Siyasi, 2023
The Enactment of Emergency Law Number 2 of 2022 on Job Creation(Job Creation Emergency Law) brings significant juridical implications to the implementation of decentralisation in Indonesia.
Mohammad Agus Maulidi
doaj   +1 more source

A Study on the Variables of Success in the National Dental Hygienist Licence Examination at D College [PDF]

open access: yesJournal of the Korea Academia-Industrial cooperation Society, 2012
The purpose of this study was to examine the variables of success in the national dental hygienist licence examination at D college. The subjects in this study were 120 dental hygiene juniors at D college located in Gangwon Province. The collected data were analyzed by the statistical package SPSS WIN 13.0 and a R2.13.2 program, and x 2 (Chi-square ...
openaire   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

National Travel Survey, 1995-2001: Special Licence Access

open access: yes, 2022
Transport, Department For (2022): National Travel Survey, 1995-2001: Special Licence Access. Florida Entomologist 105 (4), DOI: 10.5255/ukda-sn-7804-1, URL: http://dx.doi.org/10.5255/ukda-sn-7804 ...
openaire   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

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