Results 51 to 60 of about 7,978 (260)

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay   +13 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino   +25 more
wiley   +1 more source

Heaven protect us from a "UK National Licence"

open access: yes, 2015
This abomination — a proposal for a "UK National Licence" for open-access papers, making them available only in the UK, is not an April Fool joke.
openaire   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon   +9 more
wiley   +1 more source

L’intention entrepreneuriale chez les jeunes diplômés : cas des étudiants en Logistique de la Faculté Polydisciplinaire, Taroudant

open access: yesRevue Marocaine de l'Entrepreneuriat, de l'Innovation et du Management, 2016
Depuis sa création en 2010, la Faculté Polydisciplinaire de Taroudant (FPT) s’est fixée comme missionprincipale d’offrir aux étudiants l’accès aux licences professionnelles, pour une meilleure réponse aux stratégiessectorielles du développement ...
Hanane ROCHDI, Rachid EL KACHRADI
doaj   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera   +20 more
wiley   +1 more source

A clearing house for diagnostic testing: the solution to ensure access to and use of patented genetic inventions?

open access: yesBulletin of the World Health Organization
In genetic diagnostics, the emergence of a so-called "patent thicket" is imminent. Such an overlapping set of patent rights may have restrictive effects on further research and development of diagnostic tests, and the provision of clinical diagnostic ...
Esther van Zimmeren   +3 more
doaj   +1 more source

Des brise-glaces en papier ?

open access: yesTéoros, 2023
Although Switzerland is historically recognized as a country that experimented with tourism activities at an early stage and can still count on their economic and symbolic benefits today, have its researchers devoted much scientific attention to it? Have
Laurent Tissot
doaj  

NESLI - The National Electronic Site Licence Initiative……Creating a Bit of a Disturbance

open access: yesSerials: The Journal for the Serials Community, 1999
NESLI is disturbing the status quo in scholarly publishing by negotiating at national level for the provision of e-journals to UK higher education institutions. Through these negotiations and value-added services, NESLI will promote co-ordinated access, delivery and management for electronic ...
openaire   +2 more sources

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