Results 51 to 60 of about 159,536 (303)

Sparking a debate on coal: Case study on the Indian Government’s crackdown on Greenpeace

Cosmopolitan Civil Societies: An Interdisciplinary Journal, 2018
Non-governmental organisations working on rights based issues in India have recently been in the firing line of the government. The controversial Foreign Contribution Regulation Act (FCRA), originally instituted during national emergency in 1976, has ...
Ruchira Talukdar
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

L’intention entrepreneuriale chez les jeunes diplômés : cas des étudiants en Logistique de la Faculté Polydisciplinaire, Taroudant

Revue Marocaine de l'Entrepreneuriat, de l'Innovation et du Management, 2016
Depuis sa création en 2010, la Faculté Polydisciplinaire de Taroudant (FPT) s’est fixée comme missionprincipale d’offrir aux étudiants l’accès aux licences professionnelles, pour une meilleure réponse aux stratégiessectorielles du développement ...
Hanane ROCHDI, Rachid EL KACHRADI
doaj   +1 more source

National Travel Survey, 1995-2001: Special Licence Access

, 2022
Transport, Department For (2022): National Travel Survey, 1995-2001: Special Licence Access. Florida Entomologist 105 (4), DOI: 10.5255/ukda-sn-7804-1, URL: http://dx.doi.org/10.5255/ukda-sn-7804 ...
openaire   +1 more source

A Study on the Variables of Success in the National Dental Hygienist Licence Examination at D College [PDF]

Journal of the Korea Academia-Industrial cooperation Society, 2012
The purpose of this study was to examine the variables of success in the national dental hygienist licence examination at D college. The subjects in this study were 120 dental hygiene juniors at D college located in Gangwon Province. The collected data were analyzed by the statistical package SPSS WIN 13.0 and a R2.13.2 program, and x 2 (Chi-square ...
openaire   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

National licence negotiations advancing the open access transition – a view from Sweden

Insights the UKSG journal, 2018
The National Library of Sweden (NLS) has been working on advancing open access (OA) to scholarly output since 2006. In 2017 the NLS received an appropriation directive from the Government to act as a national co-ordinating body in the effort towards a transition to immediate OA for all research output by 2026.
Anna Lundén, Camilla Smith, Britt-Marie Wideberg   +2 more
openaire   +4 more sources

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source