Results 81 to 90 of about 2,960,747 (312)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
La ‘mutilation anthropologique’ et le réalignement de la littérature camerounaise Cilas Kemedjio
Tydskrif vir Letterkunde, 2016 ‘Anthropological mutilation’ and the reordering of Cameroonian literature. I argue in this article that the postcolonial existential wound, otherwise referred to by Eboussi Boulaga as the anthropological mutilation, represents the intertextual nexus that
Cilas Kemedjio
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
National grey literature cooperation model
, 2015 The National Library of Technology (NTK) has a long tradition of collecting grey literature on the national level. NTK became SIGLE system partner in the 1980s and from 2008 it has been the coordinator of the National Repository of Grey Literature (NRGL).
Vyčítalová, Hana, Pejšová, Petra
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Literature and National Formation in 19th-Century Latin America
There is more to the formation of a nation than the political reforms needed for the construction of a national state. To create a sense of national belonging, a collective consciousness among citizens is as crucial, and literature plays an important ...
Soriano Salkjelsvik, Kari, +1 more
core +1 more source
Cogent Arts & HumanitiesThe article focuses on mapping resonance between folklore narratives and the 18 character values adopted by the government of Indonesia, with the potential to facilitate integration in the New National Capital City.
Riani Riani +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
INTERCULTURAL LITERATURE IN ITALIAN LANGUAGE IN THE MIDST OF NATIONAL LITERATURES
Metodički obzori : časopis za odgojno-obrazovnu teoriju i praksu, 2013 When speaking about the literature of Croatia's Italian minority, its beginnings can be traced to 1945. Newly formed borders, the immigration influx into Italy and overseas regions, the fleeing of left-wing oriented citizens, especially intellectuals, out of Italy, a new socio-political order all lay the groundwork for the creation of a specific ...
openaire +4 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Grey Literature and National Archives
, 2019 National Archives selects the archival records from a various range of creators – from central agencies of the state administration and research institutions to individuals.
Kunt, Miroslav, Šimůnková, Karolína
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