Results 91 to 100 of about 2,885,537 (309)
Complexity Theory: An Approach to Understanding the Weak Relationships between Valparaiso’s International and Non-International Student Populations [PDF]
, 2012 The Valparaiso University campus is becoming more diverse as each year passes. The undergraduate population on campus is experiencing a rise in international admissions. Although the University has many recognized student organizational groups, including
Brewer, Michelle +2 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
A Survey of Selected National Organizations Providing Support to the Community Building Field [PDF]
, 1999 In recent years, community building has emerged as a powerful, comprehensive approach to neighborhood improvement. Increasing numbers of national and local organizations use community building to describe the ways in which they work to improve outcomes ...
Jessica Pitt +2 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
2015 Greater Washington DC Area State of Mentoring: A Report Assessing the Current State of Mentoring for Young People in Our Region [PDF]
, 2015 According to a new study conducted jointly by the United Way of the National Capital Area (United Way NCA) and Deloitte, the Washington, D.C. metro-area may be falling short when it comes to mentoring. According to the Greater Washington, D.C.
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Faulty Metrics and the Future of Digital Journalism [PDF]
, 2010 This report explores the industry of Internet measurement and its impact on news organizations working online. It investigates this landscape through a combination of documentary research and interviews with measurement companies, trade groups ...
John Kelly, Lucas Graves
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Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Collaborative Governance Assessment [PDF]
, 2012 This is the report of APFIC/FAO Regional Consultative Workshop, "Securing Sustainable Small-Scale Fisheries: Bringing together responsible fisheries and social development", held at theWindsor Suites Hotel, Bangkok, Thailand, 6-8 October 2010.
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FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source