Results 81 to 90 of about 20,538,929 (301)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

National Commission on Military, National, and Public Service: Interim Report Executive Summary

open access: yes, 2019
Executive summary for the interim report of the National Commission on Military, National, and Public Service outlining their charge, findings from information-gathering, and areas for further research, with social media contacts for public ...
United States. National Commission on Military, National, and Public Service.
core  

Dynamic portfolios via triangulated maximally filtered graph networks: a centrality-driven multi-strategy approach

open access: yesCogent Business & Management
This paper develops an empirical approach to evaluate network-based portfolio strategies relative to traditional benchmarks in the Casablanca Stock Exchange.
Younes Berouaga   +3 more
doaj   +1 more source

Exploring the Moderating Effect of Ethical Project Management Practices in the Success of IT Project: Evidence From the Public Sector [PDF]

open access: yesBusiness Ethics and Leadership
Successful digital transformations and project governance in public sector organizations now rely heavily on business ethics and responsible management. Despite years of research into project management, empirical evidence indicates that ethical project ...
Mustapha BINDGUIGNE   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Leadership Policy and Organization 3465 2009 - Macro-Europe -GLBT issues - Group 2

open access: yes, 2009
Includes descriptive metadata provided by producer in M4V file: "Leading Globally Diverse Organizations - Macro: Across Nat'l - Macro-Europe -GLBT issues - Group 2." By Vanderbilt University. This presentation from the class Leadership in Organizations
Leadership Policy and Organizations
core  

2008116.26: Student Organizations, 1959-1995 [PDF]

open access: yes, 2008
These items include materials from the office of Student Organizations at Marshall University from 1959-1995. Items were received in 2008 and include notable materials from or about Omicron Delta Kappa and various newspaper clippings. Please download the
Student Organizations
core  

Aligning governance, brand governance and social media strategies for improved organizational performance: a qualitative comparative analysis of national sport organizations

open access: yes, 2023
Purpose – This paper aims to explore the potential configurations of governance, brand governance and social media strategies leading to effective organizational performance.
Hoye, Russell   +5 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Leadership Policy and Organization 3465 2009 - Macro-EU Maternity Leave Policy-Group 4

open access: yes, 2009
Includes descriptive metadata provided by producer in M4V file: "Leading Globally Diverse Organizations - Macro: Across Nat'l - Macro-EU Maternity Leave Policy-Group 4." By Vanderbilt University.
Leadership Policy and Organizations
core  

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