Results 61 to 70 of about 20,538,929 (301)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The American Jewish Joint Distribution Committee assisted the United National Clothing Collection for War Relief with meeting their goal of providing clothing to those recovering from the ravages of World War II.
United National Clothing Collection for War Relief (U.S.)Coordinating Committee of National Jewish Organizations
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20230118: Student Organizations, 1898-2000 [PDF]
These items include materials from the office of Student Organizations at Marshall University from 1898-2000. Items were received at a much earlier time over the years, but were accessioned in 2023.
Student Organizations
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A literature review reveals that in recent years, global theories and practices of sustainable development have shifted their focus from the abstract maximization of the triple bottom line to the creation of a balanced and resilient economy.
Tetiana Kulinich +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The National Board of Farm Organizations writes to Washington State Senator Miles Poindexter to express their opposition to Senate Bill 4204, anti-strike legislation. They write that while strikes have harmful effects, they are necessary and are at times
National Board of Farm Organizations
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Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
This study investigates the influence of cultural dimensions on IT project team effectiveness through a comprehensive multi-method approach designed to connect theoretical cultural knowledge with practical implementation. Using data collected from 127 IT
Nazarii Mazur +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source

