Results 71 to 80 of about 20,538,929 (301)
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
DATA ON ARTS ORGANIZATIONS: A REVIEW AND NEEDS ASSESSMENT, WITH DESIGN IMPLICATIONS [PDF]
This project describes the data resources on arts organizations that are currently available to inform the efforts of policy makers, arts managers, and researchers working in the arts field.
Lori Morris +3 more
core
Texas National Security Review: Rethink, Reframe, Re-examine Vol. 8, Issue 3, 2025 [PDF]
TABLE OF CONTENTS: The Foundation pg.2 When Conventional Wisdom Fails Sheena Chestnut Greitens The Scholar pg.8 Lost Seoul? Assessing Pyongyang’s Other Deterrent Nicholas D. Anderson and Daryl G. Press pg.28 So What?
Texas National Security Review
core +1 more source
Sanitary Organization of Nations [PDF]
n ...
openaire +2 more sources
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Leadership Policy and Organization 3465 2009 - Macro-Brain Drain-Group 5
Includes descriptive metadata provided by producer in M4V file: "Leading Globally Diverse Organizations - Macro: Across Nat'l - Macro-Brain Drain-Group 5." By Vanderbilt University. This presentation for the course Leadership in Organizations discusses
Leadership Policy and Organizations
core
Clubs and Organizations - 1941 - United Service Organizations Card [PDF]
United Service Organizations Card of Madge Webb Rileyhttps://digitalcommons.gardner-webb.edu/fay-webb-gardner-madge-webb-riley/1030/thumbnail ...
United Service Organizations,
core
The literature review shows that, at the national level, developing a strategic toolkit for harmonious development, including for tourism and hotel-restaurant enterprises, is still at an early stage.
Тетяна Кулініч +4 more
doaj +1 more source

