Results 71 to 80 of about 547,724 (261)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Spatial analysis of coral reefs and its degradation patterns in Bunaken National Park
E3S Web of Conferences, 2019 This article will analyze the spatial pattern as well as the degradation pattern of the coral reefs in the Bunaken National Park. Bunaken National Park is a marine national park located in the Province of North Sulawesi; the park was built as means of ...
Attamimi Nafil Rabbani, Saraswati Ratna
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Addressing landscape conservation and community development through national park boundary
Global Ecology and ConservationIn the strategic expansion of protected areas, it is imperative to address sustainable development challenges by exploring innovative approaches to harmonize the conservation and utilization of ecological resources and landscape. Particularly, geological
Wang Qi, Zhong Linsheng, Yu Hu
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Forestist, 1990 National park plans are mainly prepared by tlıe lıighest competent autlıority of tlıe country. In this paper, a model which proposes a different approach to prepare national park plans has been presented.
Sümer GÜLEZ
doaj
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Theme Exploration and Sentiment Analysis of Online Reviews of Wuyishan National Park
LandThe study aimed to explore the relationship and interaction between humans and nature in specific areas. Latent Dirichlet allocation topic recognition and SnowNLP sentiment analysis were used to extract the topics and analyze the sentiments from visitors’
Wei Fu, Bin Zhou
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source