Results 131 to 140 of about 1,351,417 (359)
Mykhailo Hrushevsky and Nicolae Iorga Scholars' Struggle over the National History [PDF]
Codrul Cosminului, 2018 The article is devoted to the reconstruction of the first Ukrainian-Romanian historiographical polemic represented by leaders of the national movement Mykhailo Hrushevsky and Nicolae Iorga.
Vitalii Telvak, Vasyl Ilnytskyi
doaj
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Jan Stanislav Skrejsovsky: the Dissent in the National Party of the Czech Lands in the 1870s
RUDN Journal of World History, 2012 The article deals with the process of dissent in the National Party of the Czech Lands in the 70-s of the XIX century: two clearly defined factions within the Czech National Party had emerged: the Old Czechs and the Young Czechs.
P Nikolaevich Baratov
doaj
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Gandhiites and Socialists: The Struggle for Control of the Indian National Congress, 1931-1939. [PDF]
, 1977 James Carroll Wilson
openalex +1 more source
Revolutionary syndicalist opposition to the First World War: An international comparative reassessment [PDF]
, 2006 It has been argued that support for the First World War by the important French syndicalist organisation, the Confédération Générale du Travail (CGT) has tended to obscure the fact that other national syndicalist organisations remained faithful to their ...
Darlington, RR
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The Disquieted Heart and the Lighted Path: LeVar Burton’s Dedication Day Speech
, 2016 This Saturday past brought with it an electric sort of chill, the kind fueled by a driving breeze that lifts your jacket, steals past your socks and up your legs, worms its way through gaps in scarves and gloves, and leaves you feeling naked and afraid ...
LaRoche, Matthew D.
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source