Results 111 to 120 of about 19,191,137 (252)
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Philosophy Born of Struggle VI: Civil Liberties in the New Millennium
, 2015 Greetings begin at 05:03; Opening Statement begins at 13:50; Democracy and its Discontents begins at 35:32; The Prison Industrail Complex begins at 1:40 ...
Philosophy Born of Struggle Conference
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Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
The Rev James Lawson: The Non-Violence Struggle 11-13-2007 1 of 2
, 2007 Includes descriptive metadata provided by producer in MP4 file: "The Non-Violence Struggle - Video - The Rev James Lawson The Non-Violence Struggle 11-13-2007 1 of 2." Video of a class session.
Lawson, James M., 1928-
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Jan Stanislav Skrejsovsky: the Dissent in the National Party of the Czech Lands in the 1870s
RUDN Journal of World History, 2012 The article deals with the process of dissent in the National Party of the Czech Lands in the 70-s of the XIX century: two clearly defined factions within the Czech National Party had emerged: the Old Czechs and the Young Czechs.
P Nikolaevich Baratov
doaj
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Philosophy Born of Struggle 2005: Philosophy and Liberation
, 2015 Panel 1 and previous discussion continues at 00:00; Douglas Ficek speaks at 03:45; discussion at 30 ...
Philosophy Born of Struggle Conference
core
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source