Results 101 to 110 of about 5,098,956 (347)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
The history and politics of liberation archives at Fort Hare
, 2013 Includes bibliographical references.This thesis, the first of its kind on liberation historiography, seeks to put the liberation movements archives housed at the University of Fort Hare in context.
Maaba, Lucius Bavusile
core
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Mental Preparation of Teenagers for National Struggle
The art of fighting has been known in many nations since ancient times. Wrestling was widespread, especially in Greece, and had a permanent place in the ancient Olympic competitions.
Do‘stmurodovich, Vaxobov G‘iyos
core +1 more source
Reflections of National Struggle on Turkish novel
, 2011 The focus of this thesis has been the analysis of 26 novels whose authors display an array of ideological stances, with a view to their approaches to the Turkish National Struggle.
Tunç, Gökhan
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
, 2018 From a teaching perspective, witnessing students struggle mathematically can be distressing because all teachers want their students to be successful.
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
The destinies of the Russian minority in Gdansk (translated from Polish by L. Maltsev)
Слово.ру: балтийский акцент, 2013 This article offers a historical sketch of the life and activities of the Russian diaspora in Gdansk in the 1920-1930s. The author considers the participation of Russian emigrants in the political, business, and cultural life of Gdansk and their ...
Romanow A.
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source