Results 81 to 90 of about 5,098,956 (347)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Biochemical thresholds to differentiate mineralizing and stabilizing organic waste amendments for soil carbon management

Frontiers in Soil Science
IntroductionIdentifying organic amendments that can retain stable organic carbon is essential for improving soil health and mitigating greenhouse gas emissions.MethodsThis study assessed the carbon stability of 104 fertilizing residual materials ...
Sirine Ridene, Sirine Ridene, Lotfi Khiari, Haïthem Bahri, Mohamed Annabi, Safya Menasseri-Aubry, Rim Benjannet, Chiraz Abbes   +7 more
doaj   +1 more source

The National Front Against Poverty: The Struggle for Income Redistribution

Global Labour Journal, 2015
This article describes the campaign developed by unions, human rights organisations and other social movements in Argentina at the end of the 1990s in order to push the government to implement measures to eliminate poverty and extreme poverty.
Luis Ernesto Campos
doaj   +1 more source

The Natinal Struggle and The Armed Forces in Indonesia

, 1994
183 hal.;15 ...
Nugroho Notosusanto
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Sinop during National Struggle

, 2004
II ÖZET Bu çalışmada Milli Mücadele yıllarında Sinop'ta cereyan eden olaylar incelenmiştir. I. Bölümde Sinop'taki Milli Faaliyetler başlığı altında idari, askeri ve sosyal faaliyetler incelenmiştir. II. Bölümde Gayrimüslimlerin faaliyetleri ve buna karşı
Efe, İsmail
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Ali Fethi Okyar’ın Günlük Hâtıraları (30 Nisan 1921 – 16 Ekim 1921)

Belgeler, 1987
Türk Milli Mücadelesi ve İnkılabı Târihi'nin, Atatürk Çağı'nın ön safta gelen ünlü devlet, diplomasi ve politika adamlarından biri Ali Fethi Okyar’dır (Pirlepe, 29 Nisan 1880 - İstanbul, 7 Mayıs 1943).
Fethi Tevetoğlu
doaj  

From “struggle” to “post-revolutionary” politics: The National Party, the African National Congress, and the “great rapprochement”

Contree, 2009
Die Nasionale Party as regerende party onder Suid-Afrika se apartheidsbestel, en sy langtydse teenstander en navolger, die African National Congress, blyk onwaarskynlike onderwerpe vir ‘n vergelyking: Die een verwant aan, en bekend vir, bekrompe etniese “
Patrick J. Furlong
doaj   +1 more source