Results 1 to 10 of about 21,869 (297)

Pressure-Natriuresis Response Is Diminished in Old Age

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundAge-related alterations in renal sodium handling affect blood pressure (BP). We aimed to clarify whether the pressure-natriuresis response changes with age, leading to BP elevation.MethodsA total of 4,859 participants with normal renal function
Yang Gyun Kim   +9 more
doaj   +1 more source

Intrarenal Mechanisms of Sodium-Glucose Cotransporter-2 Inhibitors on Tubuloglomerular Feedback and Natriuresis [PDF]

open access: yesEndocrinology and Metabolism, 2023
When sodium-glucose cotransporter-2 (SGLT2) inhibitors were first introduced a decade ago, no one expected them to have substantial effects beyond their known glucose-lowering effects, until the emergence of evidence of their robust renal and ...
Eun Sil Koh, Gheun-Ho Kim, Sungjin Chung
doaj   +1 more source

Sensory Afferent Renal Nerve Activated Gαi2 Subunit Proteins Mediate the Natriuretic, Sympathoinhibitory and Normotensive Responses to Peripheral Sodium Challenges

open access: yesFrontiers in Physiology, 2021
We have previously reported that brain Gαi2 subunit proteins are required to maintain sodium homeostasis and are endogenously upregulated in the hypothalamic paraventricular nucleus (PVN) in response to increased dietary salt intake to maintain a salt ...
Jesse D. Moreira   +9 more
doaj   +1 more source

Acclimation to a High‐Salt Diet Is Sex Dependent

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Premenopausal women are less likely to develop hypertension and salt‐related complications than are men, yet the impact of sex on mechanisms regulating Na+ homeostasis during dietary salt challenges is poorly defined.
Eman Y. Gohar   +14 more
doaj   +1 more source

Sex-Specific Computational Models of Kidney Function in Patients With Diabetes

open access: yesFrontiers in Physiology, 2022
The kidney plays an essential role in homeostasis, accomplished through the regulation of pH, electrolytes and fluids, by the building blocks of the kidney, the nephrons.
Sangita Swapnasrita   +3 more
doaj   +1 more source

Effects of phenylbutazone, firocoxib, and dipyrone on the diuretic response to furosemide in horses

open access: yesJournal of Veterinary Internal Medicine, 2023
Background Treatment with phenylbutazone (nonselective COX inhibitor) decreases the diuretic and natriuretic effects of furosemide by nearly 30% but the effects of COX‐2 specific inhibitors (firocoxib) and atypical NSAIDs (dipyrone) are unknown ...
Julianne M. White   +2 more
doaj   +1 more source

Current Understanding of Pressure Natriuresis

open access: yesElectrolytes & Blood Pressure, 2021
Pressure natriuresis refers to the concept that increased renal perfusion pressure leads to a decrease in tubular reabsorption of sodium and an increased sodium excretion. The set point of blood pressure is the point at which pressure natriuresis and extracellular fluid volume are in equilibrium.
Baek, Eun Ji, Kim, Sejoong
openaire   +2 more sources

Vanadate-stimulated natriuresis [PDF]

open access: yesNature, 1978
THE observation1–3 that V(v) is a potent inhibitor of (Na+, K+)-activated renal ATPase raised the possibility that it has natriuretic and thus diuretic properties in the living animal. We report here experiments showing that it has.
I. M. Glynn   +2 more
openaire   +3 more sources

Novel Antihypertension Mechanism of β-Glucan by Corin and ANP-Mediated Natriuresis in Mice

open access: yesMycobiology, 2020
Many of the β-glucans are known to have antihypertensive activities, but, except for angiotensin-converting enzyme II inhibition, the underlying mechanisms remain unclear. Corin is an atrial natriuretic peptide (ANP)-converting enzyme.
Sun Jung Lee, Dong Hee Lee, Ha Won Kim
doaj   +1 more source

Does plasma ANP participate in natriuresis induced by a-MSH?

open access: yesBrazilian Journal of Medical and Biological Research, 1997
a-Melanocyte-stimulating hormone (a-MSH; 0.6 and 3 nmol) microinjected into the anteroventral region of the third ventricle (AV3V) induced a significant increase in diuresis without modifying natriuresis or kaliuresis. Intraperitoneal (ip) injection of a-
D.L.W. Picanço-Diniz   +5 more
doaj   +1 more source

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