GLP-1 mediated diuresis and natriuresis are blunted in heart failure and restored by selective afferent renal denervation [PDF]
Background Glucagon-like peptide-1 (GLP-1) induces diuresis and natriuresis. Previously we have shown that GLP-1 activates afferent renal nerve to increase efferent renal sympathetic nerve activity that negates the diuresis and natriuresis as a negative ...
Kenichi Katsurada +5 more
openalex +2 more sources
BTCI enhances guanylin-induced natriuresis and promotes renal glomerular and tubular effects [PDF]
Guanylin and uroguanylin are small cysteine-rich peptides involved in the regulation of fluid and electrolyte homeostasis through binding and activation of guanylyl cyclases signaling molecules expressed in intestine and kidney.
AF. Carvalho +6 more
doaj +2 more sources
Renal Function and Natriuresis-Guided Diuretic Therapy – A Pre-Specified Analysis from the PUSH-AHF Trial [PDF]
In a randomized controlled trial, we recently showed that a natriuresis‐guided diuretic approach improved natriuresis and diuresis in patients with acute heart failure (HF).
Kevin Damman +8 more
openalex +2 more sources
Acetazolamide to Increase Natriuresis in Congestive Heart Failure at High Risk for Diuretic Resistance [PDF]
To investigate the effects of acetazolamide on natriuresis, decongestion, kidney function and neurohumoral activation in acute heart failure (AHF).
Frederik H. Verbrugge +8 more
openalex +2 more sources
Natriuresis During an Acute Intravenous Sodium Chloride Infusion in Conscious Sprague Dawley Rats Is Mediated by a Blood Pressure-Independent α1-Adrenoceptor-Mediated Mechanism [PDF]
The mechanisms that sense alterations in total body sodium content to facilitate sodium homeostasis in response to an acute sodium challenge that does not increase blood pressure have not been fully elucidated.
Alissa A. Frame +9 more
doaj +2 more sources
Pressure natriuresis and the renal control of arterial blood pressure [PDF]
Jessica R. Ivy, Matthew A. Bailey
openalex +2 more sources
Gastrin and D 1 Dopamine Receptor Interact to Induce Natriuresis and Diuresis [PDF]
Yue Chen +7 more
openalex +2 more sources
We have previously reported that brain Gαi2 subunit proteins are required to maintain sodium homeostasis and are endogenously upregulated in the hypothalamic paraventricular nucleus (PVN) in response to increased dietary salt intake to maintain a salt ...
Jesse D. Moreira +9 more
doaj +1 more source
Pressure-Natriuresis Response Is Diminished in Old Age
BackgroundAge-related alterations in renal sodium handling affect blood pressure (BP). We aimed to clarify whether the pressure-natriuresis response changes with age, leading to BP elevation.MethodsA total of 4,859 participants with normal renal function
Yang Gyun Kim +9 more
doaj +1 more source

