Results 1 to 10 of about 24,274 (243)
Vanadate-stimulated natriuresis [PDF]
Nature, 1978 THE observation1–3 that V(v) is a potent inhibitor of (Na+, K+)-activated renal ATPase raised the possibility that it has natriuretic and thus diuretic properties in the living animal. We report here experiments showing that it has.
W. E. Balfour +2 more
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The mechanism of glucagon-induced natriuresis in dogs
Kidney International, 1972 The mechanism of glucagon-induced natriuresis in dogs. Although it is well established that glucagon may exert a natriuretic effect when administered to dogs, it is not clear whether this is mediated only by increments in filtered sodium or by a direct tubular effect. To study this problem we gave glucagon at 5 µg/min either i.v.
Mortimer Levy, Neil L. Starr
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The Mechanism of Denervation Natriuresis * [PDF]
Journal of Clinical Investigation, 1965 Donald E. Kamm, Norman G. Levinsky
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BTCI enhances guanylin-induced natriuresis and promotes renal glomerular and tubular effects [PDF]
Brazilian Journal of Biology, 2008 Guanylin and uroguanylin are small cysteine-rich peptides involved in the regulation of fluid and electrolyte homeostasis through binding and activation of guanylyl cyclases signaling molecules expressed in intestine and kidney.
AF. Carvalho +6 more
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Facilitation of Natriuresis with Nifedipine in Normal Humans
Journal of Cardiovascular Pharmacology, 1988 We tested the effect of dietary potassium (KCl, 20 mEq three times daily), calcium (Ca, 500 mg twice daily), sodium-potassium-dependent ATPase inhibition (digoxin), calcium channel blockade (nifedipine), and placebo on acute natriuresis in 14 normal subjects who received 2 L normal saline intravenously over 4 h.
Friedrich C. Luft +3 more
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Intrarenal Mechanisms of Sodium-Glucose Cotransporter-2 Inhibitors on Tubuloglomerular Feedback and Natriuresis [PDF]
Endocrinology and Metabolism, 2023 When sodium-glucose cotransporter-2 (SGLT2) inhibitors were first introduced a decade ago, no one expected them to have substantial effects beyond their known glucose-lowering effects, until the emergence of evidence of their robust renal and ...
Eun Sil Koh, Gheun-Ho Kim, Sungjin Chung
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Pressure-Natriuresis Response Is Diminished in Old Age
Frontiers in Cardiovascular Medicine, 2022 BackgroundAge-related alterations in renal sodium handling affect blood pressure (BP). We aimed to clarify whether the pressure-natriuresis response changes with age, leading to BP elevation.MethodsA total of 4,859 participants with normal renal function
Yang Gyun Kim +9 more
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Frontiers in Physiology, 2021 We have previously reported that brain Gαi2 subunit proteins are required to maintain sodium homeostasis and are endogenously upregulated in the hypothalamic paraventricular nucleus (PVN) in response to increased dietary salt intake to maintain a salt ...
Jesse D. Moreira +9 more
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Acclimation to a High‐Salt Diet Is Sex Dependent
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Premenopausal women are less likely to develop hypertension and salt‐related complications than are men, yet the impact of sex on mechanisms regulating Na+ homeostasis during dietary salt challenges is poorly defined.
Eman Y. Gohar +14 more
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Effects of Nifedipine on Renal and Cardiovascular Responses to Neuropeptide Y in Anesthetized Rats
Molecules, 2021 Neuropeptide Y (NPY) acts via multiple receptor subtypes termed Y1, Y2 and Y5. While Y1 receptor-mediated effects, e.g., in the vasculature, are often sensitive to inhibitors of L-type Ca2+ channels such as nifedipine, little is known about the role of ...
Angela Bischoff +2 more
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