Results 1 to 10 of about 21,869 (297)
Pressure-Natriuresis Response Is Diminished in Old Age
BackgroundAge-related alterations in renal sodium handling affect blood pressure (BP). We aimed to clarify whether the pressure-natriuresis response changes with age, leading to BP elevation.MethodsA total of 4,859 participants with normal renal function
Yang Gyun Kim+9 more
doaj +1 more source
Intrarenal Mechanisms of Sodium-Glucose Cotransporter-2 Inhibitors on Tubuloglomerular Feedback and Natriuresis [PDF]
When sodium-glucose cotransporter-2 (SGLT2) inhibitors were first introduced a decade ago, no one expected them to have substantial effects beyond their known glucose-lowering effects, until the emergence of evidence of their robust renal and ...
Eun Sil Koh, Gheun-Ho Kim, Sungjin Chung
doaj +1 more source
We have previously reported that brain Gαi2 subunit proteins are required to maintain sodium homeostasis and are endogenously upregulated in the hypothalamic paraventricular nucleus (PVN) in response to increased dietary salt intake to maintain a salt ...
Jesse D. Moreira+9 more
doaj +1 more source
Acclimation to a High‐Salt Diet Is Sex Dependent
Background Premenopausal women are less likely to develop hypertension and salt‐related complications than are men, yet the impact of sex on mechanisms regulating Na+ homeostasis during dietary salt challenges is poorly defined.
Eman Y. Gohar+14 more
doaj +1 more source
Sex-Specific Computational Models of Kidney Function in Patients With Diabetes
The kidney plays an essential role in homeostasis, accomplished through the regulation of pH, electrolytes and fluids, by the building blocks of the kidney, the nephrons.
Sangita Swapnasrita+3 more
doaj +1 more source
Effects of phenylbutazone, firocoxib, and dipyrone on the diuretic response to furosemide in horses
Background Treatment with phenylbutazone (nonselective COX inhibitor) decreases the diuretic and natriuretic effects of furosemide by nearly 30% but the effects of COX‐2 specific inhibitors (firocoxib) and atypical NSAIDs (dipyrone) are unknown ...
Julianne M. White+2 more
doaj +1 more source
Current Understanding of Pressure Natriuresis
Pressure natriuresis refers to the concept that increased renal perfusion pressure leads to a decrease in tubular reabsorption of sodium and an increased sodium excretion. The set point of blood pressure is the point at which pressure natriuresis and extracellular fluid volume are in equilibrium.
Baek, Eun Ji, Kim, Sejoong
openaire +2 more sources
Vanadate-stimulated natriuresis [PDF]
THE observation1–3 that V(v) is a potent inhibitor of (Na+, K+)-activated renal ATPase raised the possibility that it has natriuretic and thus diuretic properties in the living animal. We report here experiments showing that it has.
I. M. Glynn+2 more
openaire +3 more sources
Novel Antihypertension Mechanism of β-Glucan by Corin and ANP-Mediated Natriuresis in Mice
Many of the β-glucans are known to have antihypertensive activities, but, except for angiotensin-converting enzyme II inhibition, the underlying mechanisms remain unclear. Corin is an atrial natriuretic peptide (ANP)-converting enzyme.
Sun Jung Lee, Dong Hee Lee, Ha Won Kim
doaj +1 more source
Does plasma ANP participate in natriuresis induced by a-MSH?
a-Melanocyte-stimulating hormone (a-MSH; 0.6 and 3 nmol) microinjected into the anteroventral region of the third ventricle (AV3V) induced a significant increase in diuresis without modifying natriuresis or kaliuresis. Intraperitoneal (ip) injection of a-
D.L.W. Picanço-Diniz+5 more
doaj +1 more source