Results 11 to 20 of about 21,560 (287)
Intrarenal Mechanisms of Sodium-Glucose Cotransporter-2 Inhibitors on Tubuloglomerular Feedback and Natriuresis [PDF]
When sodium-glucose cotransporter-2 (SGLT2) inhibitors were first introduced a decade ago, no one expected them to have substantial effects beyond their known glucose-lowering effects, until the emergence of evidence of their robust renal and ...
Eun Sil Koh, Gheun-Ho Kim, Sungjin Chung
doaj +1 more source
Natriuresis-guided diuretic therapy in acute heart failure: a pragmatic randomized trial
In patients with acute heart failure, personalized dosing of a diuretic led to treatment intensification in the majority of patients and improved natriuresis, but had no effects on time to all-cause mortality or heart failure rehospitalization ...
J. T. ter Maaten +9 more
semanticscholar +1 more source
Insufficient diuretic response frequently occurs in patients admitted for acute heart failure (HF) and is associated with worse clinical outcomes. Recent studies have shown that measuring natriuresis early after hospital admission could reliably identify
J. T. ter Maaten +8 more
semanticscholar +1 more source
Acclimation to a High‐Salt Diet Is Sex Dependent
Background Premenopausal women are less likely to develop hypertension and salt‐related complications than are men, yet the impact of sex on mechanisms regulating Na+ homeostasis during dietary salt challenges is poorly defined.
Eman Y. Gohar +14 more
doaj +1 more source
Dominant factors that govern pressure natriuresis in diuresis and antidiuresis: a mathematical model
Robert Moss, Anita T. Layton
openalex +2 more sources
Current Understanding of Pressure Natriuresis
Pressure natriuresis refers to the concept that increased renal perfusion pressure leads to a decrease in tubular reabsorption of sodium and an increased sodium excretion.
E. Baek, Sejoong Kim
semanticscholar +1 more source
Effects of Nifedipine on Renal and Cardiovascular Responses to Neuropeptide Y in Anesthetized Rats
Neuropeptide Y (NPY) acts via multiple receptor subtypes termed Y1, Y2 and Y5. While Y1 receptor-mediated effects, e.g., in the vasculature, are often sensitive to inhibitors of L-type Ca2+ channels such as nifedipine, little is known about the role of ...
Angela Bischoff +2 more
doaj +1 more source
Effects of phenylbutazone, firocoxib, and dipyrone on the diuretic response to furosemide in horses
Background Treatment with phenylbutazone (nonselective COX inhibitor) decreases the diuretic and natriuretic effects of furosemide by nearly 30% but the effects of COX‐2 specific inhibitors (firocoxib) and atypical NSAIDs (dipyrone) are unknown ...
Julianne M. White +2 more
doaj +1 more source
Rationale & Objective: Heart failure treatment relies on loop diuretics to induce natriuresis and decongestion, but the therapy is often limited by diuretic resistance.
Jonathan G. Amatruda +6 more
doaj +1 more source
Sex-Specific Computational Models of Kidney Function in Patients With Diabetes
The kidney plays an essential role in homeostasis, accomplished through the regulation of pH, electrolytes and fluids, by the building blocks of the kidney, the nephrons.
Sangita Swapnasrita +3 more
doaj +1 more source

