Results 11 to 20 of about 24,274 (243)
Kidney Medicine, 2022 Rationale & Objective: Heart failure treatment relies on loop diuretics to induce natriuresis and decongestion, but the therapy is often limited by diuretic resistance.
Jonathan G. Amatruda +6 more
doaj +1 more source
Sex-Specific Computational Models of Kidney Function in Patients With Diabetes
Frontiers in Physiology, 2022 The kidney plays an essential role in homeostasis, accomplished through the regulation of pH, electrolytes and fluids, by the building blocks of the kidney, the nephrons.
Sangita Swapnasrita +3 more
doaj +1 more source
Current Understanding of Pressure Natriuresis
Electrolytes & Blood Pressure, 2021 Pressure natriuresis refers to the concept that increased renal perfusion pressure leads to a decrease in tubular reabsorption of sodium and an increased sodium excretion. The set point of blood pressure is the point at which pressure natriuresis and extracellular fluid volume are in equilibrium.
Baek, Eun Ji, Kim, Sejoong
openaire +2 more sources
Effects of phenylbutazone, firocoxib, and dipyrone on the diuretic response to furosemide in horses
Journal of Veterinary Internal Medicine, 2023 Background Treatment with phenylbutazone (nonselective COX inhibitor) decreases the diuretic and natriuretic effects of furosemide by nearly 30% but the effects of COX‐2 specific inhibitors (firocoxib) and atypical NSAIDs (dipyrone) are unknown ...
Julianne M. White +2 more
doaj +1 more source
Novel Antihypertension Mechanism of β-Glucan by Corin and ANP-Mediated Natriuresis in Mice
Mycobiology, 2020 Many of the β-glucans are known to have antihypertensive activities, but, except for angiotensin-converting enzyme II inhibition, the underlying mechanisms remain unclear. Corin is an atrial natriuretic peptide (ANP)-converting enzyme.
Sun Jung Lee, Dong Hee Lee, Ha Won Kim
doaj +1 more source
γ-Tocotrienol, a vitamin E homolog, is a natriuretic hormone precursor
Journal of Lipid Research, 2003 2,7,8-Trimethyl-2-(β-carboxyethyl)-6-hydroxychroman (γ-CEHC), a metabolite of γ-tocopherol and γ-tocotrienol, was identified as a new endogenous natriuretic factor.
Hisako Saito +5 more
doaj +1 more source
Role of cGMP in natriuresis and pressure-natriuresis [PDF]
BMC Pharmacology, 2005 Cyclic GMP (cGMP) is synthesized by renal proximal tubule (RPT) cells and is exported from these cells into the renal interstitial (RI) compartment by an organic anion transporter system. We have demonstrated that RI gGMP inhibits renal Na+ reabsorption at the renal tubule.
openaire +2 more sources
Renal potassium handling in rats with subtotal nephrectomy: modeling and analysis [PDF]
, 2018 We sought to decipher the mechanisms underlying the kidney's response to changes in K+ load and intake, under physiological and pathophysiological conditions.
Edwards, Aurelie +2 more
core +1 more source
The Childhood Role in Development of Primary Hypertension. [PDF]
, 2018 Primary hypertension is not just an adult disorder. Current US population data on children and adolescents demonstrate a prevalence of elevated blood pressure (BP) and hypertension combined of over 10%.
Falkner, Bonita
core +2 more sources
Frontiers in Physiology, 2022 Background and Purpose: European Guidelines recommend early evaluation of diuresis and natriuresis after the first administration of diuretic to identify patients with insufficient diuretic response during acute heart failure.
Belén García-Magallón +21 more
doaj +1 more source