Ovarian hormones moderate systolic hypertension in female <i>Eln</i> haploinsufficient mice. [PDF]
Dixon AJ +4 more
europepmc +1 more source
ABSTRACT Aims To quantify real‐world diagnosis and treatment of obesity in Sweden, describe cardiometabolic comorbidity burden across obesity classes, and compare long‐term cardiovascular outcomes with the general population. Materials and Methods This population‐based cohort study used the AROS (Analysis of Real‐world data of patients with Obesity in ...
Viveca Ritsinger +6 more
wiley +1 more source
Sodium-Glucose Cotransporter-2 Inhibitors Across the Glycemic Spectrum: Cardiovascular and Renal Outcomes With Mechanistic Insights. [PDF]
Abdelfadil Elgazzar R, Ramadan M.
europepmc +1 more source
Prediabetes, Malignant Ventricular Hypertrophy and Stroke: The SPRINT Trial
ABSTRACT Aims Prediabetes and left ventricular hypertrophy (LVH) are common risk factors in adults with hypertension. Whether their coexistence, particularly in the presence of subclinical myocardial injury or stress (malignant LVH), confers a heightened stroke risk is unknown.
Arnaud D. Kaze +7 more
wiley +1 more source
Semaglutide reduces murine blood pressure through the vascular smooth muscle GLP-1 receptor. [PDF]
Medak KD +14 more
europepmc +1 more source
On the Mechanism of Denervation Natriuresis
openaire +1 more source
ABSTRACT Introduction Pharmacokinetic data suggest a potential dose‐dependent effect of sodium–glucose co‐transporter‐2 (SGLT‐2) inhibitors on surrogate markers of efficacy, but the impact of SGLT‐2 inhibitor dose on renal and cardiovascular outcomes remains uncertain.
Elias John Elenjickal +5 more
wiley +1 more source
Reply to: Blood Pressure-Lowering Effect of SGLT2 Inhibitors in Patients Without Antihypertensive Treatment: A Real-World Data Analysis. [PDF]
Satoh M +6 more
europepmc +1 more source
ABSTRACT Aims Hypertension and diabetes frequently coexist, yet the net clinical impact of intentionally combining antihypertensive (AHTN) and antidiabetic (ADA) therapies on cardiovascular (CV) outcomes is uncertain. Here we quantified the effects of AHTN and ADA co‐therapy on CV and blood pressure (BP)/heart rate (HR) outcomes.
Wan Chin Hsieh +2 more
wiley +1 more source
Early Versus Delayed Diuretic Administration and Urine-Guided Strategies in Acute Decompensated Heart Failure: A Systematic Review of Clinical Outcomes. [PDF]
Muzammil R +11 more
europepmc +1 more source

