Results 191 to 200 of about 9,866 (257)

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang, Melanie Ricke‐Hoch, David Duncker, Johann Bauersachs, Dominik Berliner   +4 more
wiley   +1 more source

sGC stimulator BAY 41‐8543 improves survival and ventricular function in a rat model of doxorubicin‐induced cardiomyopathy with nephrotic syndrome

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys, Petra Škaroupková, Soňa Kikerlová, Zdeňka Vaňourková, Martina Hüttl, Olga Lenčová, Kasin Yadunandam Anandam, Svenja Stomberg, Sönke Behrends, Barbara Szeiffová Bačová, Matúš Sykora, Lisa Dietz, Peter Sandner, Luděk Červenka, Martin Štěrba   +14 more
wiley   +1 more source

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Natriuresis of starvation and glucagon.

Nutrition Reviews, 2009
exaly   +3 more sources

Volume natriuresis vs. pressure natriuresis

Acta Physiologica Scandinavica, 2004
AbstractBody fluid regulation depends on regulation of renal excretion. This includes a fast vasopressin‐mediated water‐retaining mechanism, and slower, complex sodium‐retaining systems dominated by the renin–angiotensin aldosterone cascade. The sensory mechanisms of sodium control are not identified; effectors may include renal arterial pressure ...
Bie, Peter, Wamberg, Søren, Kjølby, M.
openaire   +3 more sources

NOCTURNAL NATRIURESIS IN HYPERTHYROIDISM

Clinical Endocrinology, 1982
SUMMARYWe measured urine flow and the renal excretion of total solute, sodium, potassium and calcium in eleven patients with hyperthyroidism before and after treatment. Mean nocturnal sodium excretion was significantly greater (P < 0·05) during hyperthyroidism and was unaccompanied by any significant alterations in day time or 24‐h values.
G M, Bell, J S, Sawers, A D, Toft, A, Doig   +3 more
openaire   +2 more sources

Mechanisms of pressure natriuresis

Current Hypertension Reports, 2002
A central component of the feedback system for long-term control of arterial pressure is the pressure-natriuresis mechanism, whereby increases in renal perfusion pressure lead to decreases in sodium reabsorption and increases in sodium excretion. The specific intrarenal mechanism for the decrease in tubular reabsorption in response to increases in ...
Joey P, Granger, Barbara T, Alexander, Mayte, Llinas   +2 more
openaire   +2 more sources

Reduced natriuresis during weightlessness

The Clinical Investigator, 1993
The kidney response to weightlessness was measured in one volunteer during a 1-week space mission. Shortly after entering microgravity and later during the mission, consecutive urine sampling periods were monitored, covering in total about 50% of the inflight time.
C, Drummer, M, Heer, R A, Dressendörfer, C J, Strasburger, R, Gerzer   +4 more
openaire   +2 more sources

PRESSURE NATRIURESIS IN HYPERTENSION.

Acta Medica Scandinavica, 1981
ABSTRACTPressure natriuresis, defined as the relationship between sodium excretion and mean arterial pressure (MAP), was assessed during graded reduction of arterial pressure with nitroprusside in 16 essential hypertensives (EH). In all patients, sodium excretion fell linearly with reductions in arterial pressure (r > 0.68; p < 0.05).
openaire   +2 more sources

Exaggerated natriuresis in essential hypertension

The American Journal of Medicine, 1958
P ATIENTS with essential hypertension excrete more sodium than do normotensive patients in response to the infusion of hypertonic saline solution [7-d]. The work reported in this paper attempts to assay the role of the renal tubule in the genesis of this exaggerated natriuresis.
D S, BALDWIN, A W, BIGGS, W, GOLDRING, W H, HULET, H, CHASIS   +4 more
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Mechanism of Taurine Natriuresis in Rats

1989
Taurine, a sulfur containing amino acid, is abundant in many organs and tissues in mammals1. However, its physiological significance has been hardly understood. We reported that daily urinary taurine excretion significantly decreased in patients with essential hypertension, and administration of taurine increased urinary kallikrein and decreased blood ...
N, Kohashi, T, Okabayashi, M, Horiuchi, H, Nishiyama, T, Takenaka, R, Katori   +5 more
openaire   +2 more sources