Results 31 to 40 of about 21,560 (287)

Proximal Tubule–Specific Deletion of the NHE3 (Na+/H+ Exchanger 3) Promotes the Pressure-Natriuresis Response and Lowers Blood Pressure in Mice

HYPERTENSION, 2018
The present study directly tested the hypothesis that deletion of the NHE3 (Na+/H+ exchanger 3) selectively in the proximal tubules of the kidney lowers basal blood pressure by increasing the pressure-natriuresis response in mice.
X. Li, M. Soleimani, Dongmin Zhu, I. Rubera, M. Tauc, Xiaowen Zheng, Jianfeng Zhang, Xu Chen, J. Zhuo   +8 more
semanticscholar   +1 more source

Relationship between the actions of atrial natriuretic peptide (ANP), guanylin and uroguanylin on the isolated kidney

Brazilian Journal of Medical and Biological Research, 1999
Guanylin and uroguanylin are peptides that bind to and activate guanylate cyclase C and control salt and water transport in many epithelia in vertebrates, mimicking the action of several heat-stable bacteria enterotoxins. In the kidney, both of them have
M.S. Santos-Neto, A.F. Carvalho, L.R. Forte, M.C. Fonteles   +3 more
doaj   +1 more source

Influence of electrolyte balance on the prognosis of long-term cardiovascular events after acute coronary syndrome

Кардиоваскулярная терапия и профилактика, 2020
Aim. To assess the effect of electrolyte changes on the prognosis of long-term cardiovascular events after acute coronary syndrome (ACS).Material and methods.
E. S. Levitskaya, M. M. Batyushin, V. V. Gulchenko, A. V. Khripun, S. S. Sarkisyan, N. A. Lazutkina, R. A. Ishmakova, N. S. Zarina   +7 more
doaj   +1 more source

Klotho Ameliorates Medullary Fibrosis and Pressure Natriuresis in Hypertensive Rat Kidneys

HYPERTENSION, 2018
Renal expression of klotho is reduced in hypertension. Experiments were performed to examine whether exogenous klotho protein supplementation ameliorates pressure natriuresis in early phase of hypertension, using stroke-prone spontaneously hypertensive ...
Tsuneo Takenaka, Tsutomu Inoue, T. Miyazaki, H. Kobori, A. Nishiyama, N. Ishii, M. Hayashi, Hiromichi Suzuki   +7 more
semanticscholar   +1 more source

The exaggerated natriuresis of essential hypertension occurs independently of changes in renal medullary blood flow

Acta Physiologica, 2019
In patients with essential hypertension, abnormal renal sodium handling includes exaggerated natriuresis in response to extracellular volume expansion. We tested the hypothesis that exaggerated natriuresis is associated with increases in medullary and/or
Kasper B Assersen, P. Høilund-Carlsen, M. Olsen, S. Greve, J. C. Gam-Hadberg, P. Braad, M. Damkjaer, P. Bie   +7 more
semanticscholar   +1 more source

Protocolized Natriuresis-Guided Decongestion Improves Diuretic Response: The Multicenter ENACT-HF Study

Circulation: Heart Failure
Background: The use of urinary sodium to guide diuretics in acute heart failure is recommended by experts and the most recent European Society of Cardiology guidelines. However, there are limited data to support this recommendation.
Jeroen Dauw, K. Charaya, M. Lelonek, I. Zegri-Reiriz, Samer Nasr, Cynthia P Paredes-Paucar, A. Borbély, Fatih Erdal, R. Benkouar, M. Cobo-Marcos, G. Barge-Caballero, Varghese George, Cornelia Zara, Noel T Ross, Diane Barker, A. Lekhakul, S. Frea, A. Ghazi, D. Knappe, N. Doghmi, Milka Klincheva, I. Fialho, V. Bovolo, Hajo Findeisen, I. Alhaddad, A. Galluzzo, R. de la Espriella, R. Tabbalat, Ò. Miró, Jagdeep S Singh, P. Nijst, M. Dupont, Pieter Martens, Wilfried Mullens   +33 more
semanticscholar   +1 more source

Impaired pressure natriuresis and non‐dipping blood pressure in rats with early type 1 diabetes mellitus

Journal of Physiology, 2018
Type 1 diabetes mellitus increases cardiovascular risk; hypertension amplifies this risk, while pressure natriuresis regulates long‐term blood pressure.
G. Culshaw, Hannah M. Costello, D. Binnie, Kevin Stewart, A. Czopek, N. Dhaun, P. Hadoke, D. Webb, M. Bailey   +8 more
semanticscholar   +1 more source

Neuroendocrine regulation of salt and water metabolism

Brazilian Journal of Medical and Biological Research, 1997
Neurons which release atrial natriuretic peptide (ANPergic neurons) have their cell bodies in the paraventricular nucleus and in a region extending rostrally and ventrally to the anteroventral third ventricular (AV3V) region with axons which project to ...
S.M. McCann, C.R. Franci, A.L.V. Favaretto, J. Gutkowska, J. Antunes-Rodrigues   +4 more
doaj   +1 more source

The impact of GLP-1 receptor agonist liraglutide on blood pressure profile, hydration, natriuresis in diabetic patients with severely impaired kidney function

Scientific Reports
Chronic treatment with GLP-1R agonists may moderately lower blood pressure due to increased natriuresis and RAAS inhibition. Short-term effect of these drugs on blood pressure may be opposite and its mechanism remains unclear.
M. Wajdlich, Michał Nowicki
semanticscholar   +1 more source

Urapidil: management of complicated hypertensive crises and effects on renal function. Therapeutist’s view

Кардиоваскулярная терапия и профилактика, 2012
Aim. To compare the effectiveness of urapidil and enalaprilat in cardiac patients with complicated hypertensive crise (HC), including the effect of the medications on renal function. Material and methods.
G. P. Arutyunov, L. G. Oganezova
doaj   +1 more source