Results 51 to 60 of about 24,274 (243)

Renal effects of uroguanylin and guanylin in vivo

open access: yesBrazilian Journal of Medical and Biological Research, 1999
Uroguanylin and guanylin are newly discovered endogenous heat-stable peptides that bind to and activate a membrane bound guanylyl cyclase signaling receptor (termed guanylyl cyclase C; GC-C).
S.L. Carrithers   +10 more
doaj   +1 more source

Toward quantification of loop diuretic responsiveness for congestive heart failure

open access: yesJournal of Veterinary Internal Medicine, 2023
Diuretics, such as furosemide, are routinely administered to dogs with congestive heart failure (CHF). Traditionally, dose and determination of efficacy primarily are based on clinical signs rather than quantitative measures of drug action.
Mark A. Oyama, Darcy Adin
doaj   +1 more source

Evaluating techniques in tissue clarification using CLARITY imaging and investigating where sodium is sensed in the body [PDF]

open access: yes, 2016
OBJECTIVE: Previous studies have shown the significant contribution of sympathoinhibition in response to sodium loading to prevent increases in mean arterial blood pressure in salt resistant phenotypes.
Neal, Christopher Matthew
core   +1 more source

Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability [PDF]

open access: yes, 2017
Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability. Am J Physiol Renal Physiol 313: F174 –F183, 2017.
Chen, Ying   +3 more
core   +1 more source

Aldosterone Decreases Vasopressin-Stimulated Water Reabsorption in Rat Inner Medullary Collecting Ducts

open access: yesCells, 2020
Aldosterone indirectly regulates water reabsorption in the distal tubule by regulating sodium reabsorption. However, the direct effect of aldosterone on vasopressin-regulated water and urea permeability in the rat inner medullary collecting duct (IMCD ...
Yanhua Wang   +4 more
doaj   +1 more source

Attenuated pressure natriuresis in hypertensive rats

open access: yesKidney International, 1982
We studied the isolated blood-free perfused nonclipped kidneys from the 2-kidney Goldblatt hypertensive rat model (GHR) to evaluate intrinsic excretory responses to changes in perfusion pressure. We examined kidneys from 10 control rats (in vivo systolic BP 110 +/- 3.6 mm Hg), from 9 rats with nonmalignant hypertension (HBP) (in vivo systolic BP 158 +/-
Joyce B. Watkins   +4 more
openaire   +3 more sources

Transforming Diabetes Care: The Molecular Pathways through Which GLP1-RAs Impact the Kidneys in Diabetic Kidney Disease

open access: yesBiomedicines
Diabetic kidney disease (DKD) is a substantial complication of type 2 diabetes (T2D), presenting challenges in chronic kidney disease (CKD) management.
Merita Rroji, Goce Spasovski
doaj   +1 more source

Tamoxifen Decreases Lithium-Induced Natriuresis in Rats With Nephrogenic Diabetes Insipidus

open access: yesFrontiers in Physiology, 2018
Lithium is widely used in the treatment of bipolar affective disorders, but often causes nephrogenic diabetes insipidus (NDI), a condition characterized by a severe urinary concentrating defect. Lithium-induced NDI is associated with dysregulation of the
Stine Julie Tingskov   +3 more
doaj   +1 more source

Genetic Deletion of P2Y2 Receptor Offers Long-Term (5 Months) Protection Against Lithium-Induced Polyuria, Natriuresis, Kaliuresis, and Collecting Duct Remodeling and Cell Proliferation

open access: yesFrontiers in Physiology, 2018
Chronic lithium administration for the treatment of bipolar disorder leads to nephrogenic diabetes insipidus (NDI), characterized by polyuria, natriuresis, kaliuresis, and collecting duct remodeling and cell proliferation among other features. Previously,
Yue Zhang   +16 more
doaj   +1 more source

Effect of salt intake on clinical course and hemodynamics in patients with hypertrophic cardiomyopathy

open access: yesКардиоваскулярная терапия и профилактика, 2022
Aim. To evaluate the relationship between the salt intake (NaCl) and the clinical and hemodynamic parameters in patients with hypertrophic cardiomyopathy (HCM).Material and methods.
N. G. Poteshkina   +4 more
doaj   +1 more source

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