This review synthesises current knowledge on gut microbiome involvement in obesity and hypertension, evaluates microbiome‐based therapeutic strategies, and identifies critical research gaps to guide future investigations aimed at mitigating the dual pandemics.
Andrej Belančić +7 more
wiley +1 more source
Towards routine monitoring for myocardial injury after noncardiac surgery. [PDF]
Dissanayake D +3 more
europepmc +1 more source
MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen +4 more
wiley +1 more source
Logistic regression analysis of factors influencing NT-proBNP expression levels in patients with unstable angina pectoris and intervention strategies. [PDF]
Sun Z.
europepmc +1 more source
ANP-ing Up Diabetes: Impaired Natriuretic Peptide Action in Muscle Forms a Mechanistic Link Between Obesity and Diabetes [PDF]
Cleasby, M E
core +2 more sources
Hederagenin Attenuates Cardiac Remodeling by Targeting Phosphodiesterase 9A
ABSTRACT Background and Aim New therapeutic strategies for heart failure are urgently needed. The protective effects of cyclic guanosine monophosphate (cGMP)—protein kinase G (PKG) pathway on heart have been widely reported. Despite phosphodiesterase 9A (PDE9A) inhibitors combating cardiac remodeling, clinically available drugs are lacking. Hederagenin
Liqian Chen +16 more
wiley +1 more source
Evaluation of predictors indicating paroxysmal atrial fibrillation in patients with acute ischemic strokes: the Find-AF<sub>RANDOMISED</sub> trial. [PDF]
Weber-Krüger M +10 more
europepmc +1 more source
Processing and clearance of atrial natriuretic factor [PDF]
Gerbes, Alexander L. +2 more
core +1 more source
Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng +8 more
wiley +1 more source
Venous thromboembolism and bleeding in cancer patients: role of inflammatory and cardiac biomarkers. [PDF]
Roy DC +6 more
europepmc +1 more source

