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The Value of Biomarkers in the Diagnosis and Prognosis of Heart Failure in Older Age
The search for reliable algorithms for diagnosing heart failure with preserved left ventricular ejection fraction (LVEF) in elderly patients is an urgent problem due to the low specificity of clinical manifestations and the peculiarities of involutive ...
V. N. Larina, V. I. Lunev
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The effect of local injection of atrial (ANP), brain (BNP) and C-type (CNP) natriuretic peptides and an ANP antagonist (HS-142-1) on testicular microcirculation and vasomotion was studied using laser Doppler flowmetry.
O. Collin, E. Lissbrant, Anders Bergh
semanticscholar +1 more source
Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure [PDF]
BACKGROUND: The compensatory actions of the endogenous natriuretic peptide system require adequate processing of natriuretic peptide pro‐hormones into biologically active, carboxyl‐terminal fragments.
Barton, P+5 more
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Detection of C-type natriuretic peptide (CNP) transcript in the rat heart and immune organs [PDF]
Previous studies suggested the expression of mRNA, coding for CNP, exclusively in the central nervous system. In the present study, using the polymerase chain reaction (PCR) technique instead of the less sensitive Northern blot hybridization, CNP ...
Gerbes, Alexander L.+3 more
core +1 more source
Brain Natriuretic Peptides as Biomarkers for Atherosclerosis [PDF]
Identification of atherosclerotic risk factors provides targets for development of preventive therapies. Risk factor assessment permits evaluation of an individual's prospective risk of coronary heart disease (CHD). However, it has become apparent that traditional risk factors may not predict CHD in some patients.
Kellan E. Ashley+2 more
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Background. B-type natriuretic peptide has been shown to be a very sensitive and specific marker of heart failure. In this study, we aimed to investigate the effect of percutaneous closure of ventricular septal defects with Amplatzer septal occluders on ...
Yuksel Kaya+11 more
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Physiology and clinical significance of natriuretic hormones
The natriuretic system consists of the atrial natriuretic peptide (ANP) and four other similar peptides including the wrongly named brain natriuretic peptide (BNP). Chemically they are small peptide hormones predominantly secreted by the cardiac myocytes
Sandeep Chopra+3 more
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Molecular Implications of natriuretic peptides in the protection from hypertension and target organ damage development [PDF]
The pathogenesis of hypertension, as a multifactorial trait, is complex. High blood pressure levels, in turn, concur with the development of cardiovascular damage.
Forte, Maurizio+3 more
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Brain Natriuretic Peptide in Hypertension.
Brain natriuretic peptide (BNP) was first identified in the porcine brain and later isolated from porcine, rat, and human hearts. In humans, plasma BNP concentrations are progressively elevated with increasing severity of hypertension, particularly when left ventricular hypertrophy (LVH) is present.
Tadanao Takeda, Masakazu Kohno
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Natriuretic peptides and their usefulness in clinical practise
Natriuretic peptides are peptic hormones produced by atrial and ventricular myocytes, and by endothelium of blood vessels, that take part in homeostatic control of water and sodium levels, but also potassium transport, lipolysis in adipocytes and blood ...
Aleksandra Skałecka+5 more
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