Results 21 to 30 of about 96,151 (287)

Molecular Mechanism of Blood Pressure Regulation through the Atrial Natriuretic Peptide

Biology, 2022
Natriuretic peptides, including atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP), have cardioprotective effects and regulate blood pressure in mammals.
Takeshi Tokudome, Kentaro Otani
doaj   +1 more source

The T2238C human atrial natriuretic peptide molecular variant and the risk of cardiovascular diseases [PDF]

, 2018
Atrial natriuretic peptide (ANP) is a cardiac hormone which plays important functions to maintain cardio-renal homeostasis. The peptide structure is highly conserved among species. However, a few gene variants are known to fall within the human ANP gene.
Bianchi, Franca, Forte, Maurizio, Marchitti, Simona, Rubattu, Speranza, Sciarretta, Sebastiano, Volpe, Massimo   +5 more
core   +5 more sources

Inefficient constitutive inhibition of P2X3 receptors by brain natriuretic peptide system contributes to sensitization of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine

Molecular Pain, 2016
Background On trigeminal ganglion neurons, pain-sensing P2X3 receptors are constitutively inhibited by brain natriuretic peptide via its natriuretic peptide receptor-A. This inhibition is associated with increased P2X3 serine phosphorylation and receptor
Anna Marchenkova PhD, Sandra Vilotti PhD, Niels Ntamati MS, Arn MJM van den Maagdenberg PhD, Andrea Nistri MD   +4 more
doaj   +1 more source

Serum brain natriuretic peptide (BNP) and N-terminal brain natriuretic peptide (NT-proBNP) in heart valve disease

SA Heart Journal, 2017
Serum levels of natriuretic peptides (BNP and NT- proBNP) are known to increase in cardiac failure, and aid in the diagnosis and management of such patients.
J.A. Moolman, L. Du Preez, G. Rossouw
doaj   +1 more source

Feasibility study of intraoperative pericardial fluid biomarkers and length of stay after cardiac surgeryCentral MessagePerspective

JTCVS Techniques, 2023
Objective: Pericardial fluid biomarkers reflect the physiologic state of the myocardium. Previously, we showed a sustained increase in pericardial fluid biomarkers compared with blood in the 48 hours after cardiac surgery.
Lee A. Goeddel, MD, MPH, Ahmed Zaky, MD, MPH, Inmaculada Aban, PhD, Chad Steele, PhD, James F. George, PhD, Spencer J. Melby, MD, Louis J. Dell'Italia, MD   +6 more
doaj   +1 more source

Natriuretic peptides and their usefulness in clinical practise

Journal of Education, Health and Sport, 2020
Natriuretic peptides are peptic hormones produced by atrial and ventricular myocytes, and by endothelium of blood vessels, that take part in homeostatic control of water and sodium levels, but also potassium transport, lipolysis in adipocytes and blood ...
Aleksandra Skałecka, Karol Krupa, Aleksandra Słabczyńska, Małgorzata Romaniuk, Konrad Suswał, Janusz Milanowski   +5 more
doaj   +1 more source

Rationale and design of the GUIDE-IT study: Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure. [PDF]

, 2014
OBJECTIVES: The GUIDE-IT (Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure) study is designed to determine the safety, efficacy, and cost-effectiveness of a strategy of adjusting therapy with the goal of achieving and
Adams, Kirkwood F., Ahmad, Tariq, Anstrom, Kevin J., Cooper, Lawton S., Desvigne-Nickens, Patrice, Ezekowitz, Justin A., Felker, G. Michael, Fiuzat, Mona, Houston-Miller, Nancy, Januzzi, James L., Leifer, Eric S., Mark, Daniel B., O\u27Connor, Christopher M., Paynter, Gayle, Piña, Ileana L., Whellan, David J.   +15 more
core   +3 more sources

Natriuretic peptides are neuroprotective on in vitro models of PD and promote dopaminergic differentiation of hiPSCs-derived neurons via the Wnt/β-catenin signaling

Cell Death Discovery, 2021
Over the last 20 years, the efforts to develop new therapies for Parkinson’s disease (PD) have focused not only on the improvement of symptomatic therapy for motor and non-motor symptoms but also on the discovering of the potential causes of PD, in order
Daniela Giovannini, Federica Andreola, Paola Spitalieri, Ewa Krystyna Krasnowska, Arianna Colini Baldeschi, Simona Rossi, Federica Sangiuolo, Mauro Cozzolino, Annalucia Serafino   +8 more
doaj   +1 more source

Natriuretic peptides and integrated risk assessment for cardiovascular disease. an individual-participant-data meta-analysis [PDF]

, 2016
BACKGROUND: Guidelines for primary prevention of cardiovascular diseases focus on prediction of coronary heart disease and stroke. We assessed whether or not measurement of N-terminal-pro-B-type natriuretic peptide (NT-proBNP) concentration could enable ...
Adam S, Butterworth, Andreas, Luchner, Angela M, Wood, Brendan, M. Everett, Børge G, Nordestgaard, Caroline, N. Kistorp, Christie M, Ballantyne, Christopher, Defilippi, Daniel F, Freitag, Daniel, Levy, Demosthenes, B. Panagiotakos, DI ANGELANTONIO, EMANUELE, Frank, Kee, Goya Wannamethee, S, James A, de Lemos, Jari A. Laukkanen, Maryam Kavousi, Jens, Rosenberg, Johan, Ärnlöv, John, Danesh, Jonas, Andersson, Jorge R, Kizer, Juan Pablo, Casas, Jukka, T. Salonen, Jussi, Kauhanen, Lars, Lind, Lisa, Pennells, Lori B, Daniels, Mary, Cushman, Michael, Hecht Olsen, Michael, Sweeting, Nancy, R. Cook, Naveed, Sattar, Olle, Melander, Oscar, H. Franco, Paul M, Ridker, Pei, Gao, Peter, Willeit, Rajiv, Chowdhury, RUBATTU, Speranza Donatella, Rudolf, A. de Boer, Sarah, A. Spackman, Simon G, Thompson, Stefan, Kiechl, Stella, Trompet, Stephen Kaptoge, Paul Welsh, Stephen, Burgess, Suzanne, Judd, Thomas, Mueller, Torben, Jørgensen, Toshiharu, Ninomiya, Veikko, Salomaa, Vijay, Nambi, Vilmundur, Gudnason, Wayne, D. Rosamond   +53 more
core   +1 more source

A Multi-marker Model for Predicting Decompensated Heart Failure in Patients with Prior Acute Myocardial Infarction [PDF]

, 2020
The aim of the study was to assess the prognostic value of determining the plasma concentration of NT-proBNP and ST2 in the patients with decompensated HF and prior acute myocardial infarction and their combination in this category of patients.Materials ...
Levandovska, K. (Khrystyna)
core   +3 more sources