Results 41 to 50 of about 97,327 (272)

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

TNF-α Regulates Natriuretic Peptides and Aquaporins in Human Bronchial Epithelial Cells BEAS-2B

Mediators of Inflammation, 2013
Postoperative-fluid retention is a severe complication frequently reported in patients undergoing major surgical procedures. The complex network of molecules involved in such a severe surgery-induced condition remains poorly understood.
Letizia Mezzasoma, Lucio Cagini, Cinzia Antognelli, Francesco Puma, Eugenio Pacifico, Vincenzo Nicola Talesa   +5 more
doaj   +1 more source

The level of NT-proBNP in ambulatory patients with chronic heart failure with preserved ejection fraction of the left ventricle [PDF]

Терапевтический архив, 2018
The prevalence of chronic heart failure (CHF) remains high. Echocardiography is a reliable method of diagnosing heart failure. Determination of brain natriuretic peptide allows to identify patients with the most probable diagnosis of heart failure, which
V V Kirillova, L A Sokolova, V N Meshchaninov, V I Pershanova   +3 more
doaj   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

The expression of MALAT1, plasma brain natriuretic peptide, and Tei index in sepsis-induced myocardial injury

Journal of Cardiothoracic Surgery
Purpose We sought to investigate the expression of MALAT1, plasma brain natriuretic peptide, and Tei index in sepsis-induced myocardial injury. Methods The current retrospective analysis focused on 146 sepsis patients admitted to our hospital from ...
Guangqing Huang, Wenzi Yang, Xu Zhao, Yong Bai, Xing Jiang, Jie Liu   +5 more
doaj   +1 more source

Genome-Wide Association with Select Biomarker Traits in the Framingham Heart Study [PDF]

, 2007
BACKGROUND: Systemic biomarkers provide insights into disease pathogenesis, diagnosis, and risk stratification. Many systemic biomarker concentrations are heritable phenotypes.
Benjamin, Emelia J., Booth, Sarah L., Dupuis, Josée, Govindaraju, Diddahally R., Kathiresan, Sekar, Keaney, John F., Keyes, Michelle J., Larson, Martin G., Lin, Jing-Ping, Lunetta, Kathryn L., Meigs, James B., Robins, Sander J., Rong, Jian, Schnabel, Renate, Vasan, Ramachandran S., Vita, Joseph A., Wang, Thomas J., Wilson, Peter W. F., Wolf, Philip A.   +18 more
core   +3 more sources

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Evaluation of Tissue Doppler Echocardiographic Imaging findings in children with pulmonary hypertension

The Turkish Journal of Pediatrics, 2017
Tissue Doppler Imaging has become an important prognostic marker that can be used in follow-up and determination of the prognosis in pulmonary hypertension patients.
Alper Akın, Dursun Alehan, Hayrettin Hakan Aykan, Süheyla Özkutlu, Sema Özer, Tevfik Karagöz   +5 more
doaj   +1 more source

Brain natriuretic peptide: Diagnostic potential in dogs [PDF]

Veterinarski Glasnik, 2009
The endocrine role of the heart is evident in the secretion of noradrenaline and natriuretic peptides. The secretion of natriuretic peptides presents a useful mechanism for different conditions of cardiac dysfunction.
Spasojević-Kosić Ljubica
doaj   +1 more source

Resetting the neurohormonal balance in heart failure (HF). the relevance of the natriuretic peptide (NP) system to the clinical management of patients with HF [PDF]

, 2017
The natriuretic peptide (NP) system, which includes atrial natriuretic peptide, B-type natriuretic peptide, and C-type natriuretic peptide, has an important role in cardiovascular homeostasis, promoting a number of physiological effects including ...
Rubattu, Speranza Donatella, Triposkiadis, Filippos   +1 more
core   +2 more sources