Results 221 to 230 of about 123,362 (289)

The anti‐fibrotic effects of novel heart failure pharmacotherapies in advanced heart failure patients

British Journal of Pharmacology, EarlyView.
Background and Purpose Novel heart failure (HF) pharmacotherapies, including angiotensin receptor‐neprilysin inhibitor (ARNI) and sodium‐glucose cotransporter 2 inhibitors (SGLT2is), may confer cardiovascular benefits by attenuating myocardial fibrosis. However, direct evidence from human failing myocardial samples is limited.
Dávid Nagy, Tamás Radovits, Tímea Bálint, Zoltán Horváth, Petra Kocsis‐Balogh, Ákos Gergely Tóth, Attila Oláh, Alex Ali Sayour, Bálint András Barta, Béla Merkely, Mihály Ruppert   +10 more
wiley   +1 more source

Evaluation of N-terminal Pro-B-Type Natriuretic Peptide (NT-proBNP) as a Biomarker of Cardiac Dysfunction Across Heart Failure Phenotypes. [PDF]

Cureus
Fatima A, Haris Mansoor M, Munir A, Ali B, Maryam H, Tariq MS.   +5 more
europepmc   +1 more source

A combination of increased Rho kinase activity and N-terminal pro-B-type natriuretic peptide predicts worse cardiovascular outcome in patients with acute coronary syndrome

, 2012
Ming Dong, James K. Liao, Bryan P. Yan, Ruijie Li, Mang Zhang, Cheuk‐Man Yu   +5 more
openalex   +2 more sources

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu, Xingju Zou, Yang Zheng, Chen Sun, Cheng Peng   +4 more
wiley   +1 more source

Left Atrial Remodeling Parameters and Brain Natriuretic Peptide Levels in Nonvalvular Atrial Fibrillation. [PDF]

J Saudi Heart Assoc
Amin O, Alaarag A, Khattab H, Abou-Omar M.   +3 more
europepmc   +1 more source

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi, Raimondo Ascione, Shazia Khan, Thomas Johnson, Eva Sammut, Vito Domenico Bruno, Daniel Baz Lopez, Carol‐Anne James, Joanna Simpson, Natalie Z. Homer, Michael Millar, Trisha Singh, Alex von Kreigsheim, Nick L. Mills, Brian R. Walker, Ruth Andrew, Scott P. Webster, Andrew Whittaker, Adrian Freeman, Gillian A. Gray   +19 more
wiley   +1 more source

Effects of Perioperative Recombinant Human Brain Natriuretic Peptide in Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-Analysis. [PDF]

Rev Cardiovasc Med
Shao J, Wang L, Shao C, Wang Y, Li J, Luo J, Du Z, Hou X.   +7 more
europepmc   +1 more source

B-type natriuretic peptide in patients after percutaneous trans-coronary-sinus mitral annuloplasty

, 2014
Tomasz Siminiak, Olga Jerzykowska, Michał Kuzemczak, Andrzej Szyszka, Piotr Kałmucki, Artur Baszko   +5 more
openalex   +2 more sources

Disproportional ventilatory response to incremental exercise in individuals with cerebral palsy

Developmental Medicine &Child Neurology, EarlyView.
Individuals with cerebral palsy demonstrate a disproportionate ventilatory response during incremental exercise. Compared with typically developing peers, respiratory frequency increases earlier and at comparable exercise intensities, contributing to higher perceived exertion and reduced ventilatory efficiency. At task failure, respiratory frequency is
Linnéa Corell, Emma Hjalmarsson, Rodrigo Fernandez‐Gonzalo, Annika Kruse, Sebastian Edman, Asta Kizyte, Rouli Wang, Arnoud Edelman Bos, Peder Sörensson, Eva Pontén, Petra E. M. van Schie, Annemieke I. Buizer, Jessica Norrbom, Daniele A. Cardinale, Ferdinand von Walden   +14 more
wiley   +1 more source

Finerenone ameliorates diabetic kidney disease exacerbated by deletion of natriuretic peptide/guanylyl cyclase-A signaling and dietary high-protein load. [PDF]

Sci Rep
Inoue Y, Ishii A, Ishimura T, Yamada H, Sugioka S, Handa T, Ikushima A, Nishio H, Kato Y, Ohno S, Nakagawa Y, Kuwahara K, Matsusaka T, Tokudome T, Yanagita M, Yokoi H.   +15 more
europepmc   +1 more source