Results 231 to 240 of about 171,856 (307)

Action on elevated natriuretic peptide in primary care: a retrospective cohort study. [PDF]

open access: yesBJGP Open
Vermeer CJ   +6 more
europepmc   +1 more source

Effects of Dapagliflozin on Cardiovascular Outcomes in Patients With Type 2 Diabetes at Risk of Liver Fibrosis

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The fibrosis‐4 (FIB‐4) score is used to identify risk of advanced liver fibrosis. This post hoc analysis investigated its prognostic value for cardiovascular (CV) outcomes and its relevance to the effects of dapagliflozin. Materials and Methods DECLARE‐TIMI 58 was a randomised, placebo‐controlled phase 3 trial investigating dapagliflozin ...
Jan Oscarsson   +12 more
wiley   +1 more source

Associations Between Serum N-Terminal Pro-Brain Natriuretic Peptide Levels and the Prevalence of Sarcopenia in Middle-Aged and Older Japanese Adults: A Population-Based Cross-Sectional Study. [PDF]

open access: yesGeriatr Gerontol Int
Sato R   +14 more
europepmc   +1 more source

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

open access: yesThe FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy   +7 more
wiley   +1 more source

Bioelectrical Impedance in Pediatric Dialysis: Clinical Applications, Limitations, and Opportunities

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background Optimizing fluid and nutritional management is a cornerstone of care for children with end‐stage kidney disease on dialysis. Inaccurate assessment of hydration status contributes to hypertension, fluid overload, and increased cardiovascular risk, while masking important changes in muscle and fat compartments that affect growth and ...
Marisa Juarez‐Calderon   +2 more
wiley   +1 more source

Immune checkpoint inhibitor cardiomyotoxicity: a case series of five patients and development of a clinical management algorithm

open access: yesInternal Medicine Journal, EarlyView.
Abstract Immune checkpoint inhibitor (ICI) therapies have revolutionised the management of a range of malignancies. However, the syndrome of ICI induced cardiomyotoxicity, also reported as triple “M” syndrome (myasthenia gravis, myositis and myocarditis) is an unfortunate severe consequence in up to 1%–2% of patients receiving ICI, with an associated ...
S. Z. Xie   +14 more
wiley   +1 more source

The Effects of the Natriuretic Peptide System on Alveolar Epithelium in Heart Failure. [PDF]

open access: yesInt J Mol Sci
Knany Y   +5 more
europepmc   +1 more source

Clinical Prediction Model for Unsuccessful Left Bundle Branch Area Pacing

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
A clinical prediction model based on NIVCD, interventricular septal thickness, and right atrial area enables individualized estimation of unsuccessful LBBAP and may help guide procedural strategy. ABSTRACT Introduction Left bundle branch area pacing (LBBAP) has rapidly become a preferred form of cardiac physiologic pacing; however, predictors of ...
Yousaku Okubo   +13 more
wiley   +1 more source

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