Results 231 to 240 of about 1,178,585 (315)

Elevated B-Type Natriuretic Peptide as a Predictor of Unfavorable Outcomes in Post-Acute Stroke Patients. [PDF]

Circ Rep
Kai G, Ogura K, Ueno K, Sato K, Miki T, Noda T, Yamashita M, Kanai M, Nozoe M, Kamiya K.   +9 more
europepmc   +1 more source

MCL‐1 inhibition triggers a largely reversible cardiac stress signature in a humanised mouse model

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Myeloid cell leukaemia‐1 (MCL‐1) is an essential anti‐apoptotic protein and a promising therapeutic target in oncology. Early clinical studies of MCL‐1 inhibitors reported unexpected elevations in cardiac troponin, raising concerns about potential cardiotoxicity.
Markus B. Heckmann, Zsanett Papdi, Nils J. Strauch, Daniel Finke, Marc‐Steffen Raab, Antje Blank, Norbert Frey, Lorenz H. Lehmann   +7 more
wiley   +1 more source

Clinical efficacy and safety of recombinant human brain natriuretic peptide in the treatment of sepsis complicated by heart failure: a systematic review and meta-analysis. [PDF]

BMC Cardiovasc Disord
Liu W, Zeng R, Zhang Z, Kong X, Guo L, Cai B.   +5 more
europepmc   +1 more source

Asthma and Multimorbidity Amongst Ethnic Minority Groups in High Income Countries

Clinical &Experimental Allergy, EarlyView.
There is a tight intersection between asthma, deprivation, ethnicity, multimorbidity and poor clinical outcomes. An integrated, holistic and culturally tailored approach is needed to improve clinical outcomes amongst ethnic minority groups with asthma and multimorbidity. ABSTRACT Asthma is one of the commonest noncommunicable diseases worldwide.
Mamidipudi Thirumala Krishna, Saibal Moitra, Anna Freeman, Ben Ainsworth, Rebecca Knibb, Ramesh Kurukulaaratchy, Adel H. Mansur   +6 more
wiley   +1 more source

Structural characterization of atrial natriuretic peptide amyloid fibrils from patients with atrial fibrillation. [PDF]

Nat Commun
Broggini L, Piccoli M, Chaves-Sanjuan A, Bonnet DMV, Cirillo F, Visentin C, Sonzini F, Signorelli P, Lavota I, Milazzo M, Nonnis S, Menicanti L, Ciconte G, Pappone C, Anastasia L, Ricagno S.   +15 more
europepmc   +1 more source

GLP‐1‐Based Therapies in Type 1 Diabetes: Emerging Evidence on Cardiovascular, Renal, and Safety Outcomes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Individuals living with type 1 diabetes (T1D) are at increased risk for cardiovascular (CV) and renal complications, yet therapeutic strategies specifically targeting cardiorenal risk reduction in this population remain limited. The role of glucagon‐like peptide‐1 (GLP‐1)‐based therapies in T1D remains unclear.
Anastasios Tentolouris, Djordje S. Popovic, Alexandros L. Liarakos, Alexandros Briasoulis, Nikolaos Papanas, Theocharis Koufakis   +5 more
wiley   +1 more source

B-Type Natriuretic Peptide as a Marker of Subclinical Heart Disease in a High-Burden Emergency Department Population With Sustained Asymptomatic Hypertension. [PDF]

Int J Hypertens
Souffront K, Nelson BP, Lukas M, Garay HR, Shubeck C, Gordon L, Loo GT, Degtyar A, Wilder M, Iddrisu H, Coleman B, Richardson LD.   +11 more
europepmc   +1 more source

Cardiovascular Autonomic Neuropathy and Indices of Heart Failure in Type 2 Diabetes: The CANCAN Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To quantify the association between cardiovascular autonomic neuropathy (CAN) and heart failure (HF) in individuals with type 2 diabetes (T2D). Materials and Methods Two hundred T2D individuals were recruited from two Danish outpatient clinics between 2021–2024. CAN was defined by abnormal cardiovascular autonomic reflex test results.
Jonas R. Schaarup, Lasse Bjerg, Christian S. Hansen, Daniel R. Witte, Henrik H. Thomsen, Jesper Fleischer, Rodica Pop‐Busui, Signe T. Andersen   +7 more
wiley   +1 more source

Subclinical Primary Aldosteronism Is Characterized by Maladaptive Natriuretic Peptide and Adrenal Hormonal Physiology.

J Clin Endocrinol Metab
Parisien-La Salle S, Brown JM, Mahrokhian S, Hanna I, Honzel B, Tsai LC, Newman AJ, Wang TJ, Vaidya A.   +8 more
europepmc   +1 more source

The Anti-Apoptotic Effect of C-Type Natriuretic Peptide and the Regulation of NPPC in Porcine Ovarian Granulosa Cells. [PDF]

Int J Mol Sci
Liu X, Lu J, Zeng J, An L, Tian J, Xi G.
europepmc   +1 more source