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Physiology of Natriuretic Peptides

Journal of Internal Medicine, 1994
De Bold’s discovery 16 yr ago of an atrial tissue factor (1) with strong natriuretic activity understandably captured the imagination of renal physiologists seeking the elusive “third factor” (2) and new insights into sodium regulation. However, as well as natriuresis, de Bold’s original experiments showed that the atrial extract also caused ...
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Atrial natriuretic peptide

Journal of Cardiothoracic Anesthesia, 1989
This report has reviewed some of the cardiovascular aspects of ANP. The emergence of the heart as an endocrine organ requires that numerous questions be asked with regard to the importance of ANP to anesthesia and surgery. It is clear that the interaction of the hormone with other vasoactive compounds, including anesthetic agents, requires further ...
R. W. McIntyre, Debra A. Schwinn
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The natriuretic peptides in hypertension

Current Opinion in CARDIOLOGY, 1995
The natriuretic peptide family consists of three members: atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide. Atrial and brain natriuretic peptides possess similar effects, causing natriuresis, vasodilation, and suppression of the renin-angiotensin-aldosterone system.
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The natriuretic-peptide family

The Lancet, 1997
The discovery in the early 1980s of atrial natriuretic peptide, a circulating peptide with natriuretic/diuretic and vasorelaxant properties was greeted with excitement since the existence of a humoral link between heart and kidney had long been predicted.
Juliana Redondo   +2 more
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The Natriuretic Peptides for Hypertension Treatment

High Blood Pressure & Cardiovascular Prevention, 2021
Hypertension is a common pathological condition predisposing to a higher occurrence of cardiovascular diseases and events. Unfortunately, treatment of hypertension is still suboptimal worldwide. More efforts are needed to implement the availability of anti-hypertensive drugs.
Rubattu S., Gallo G.
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The action of two natriuretic peptides (atrial natriuretic peptide and brain natriuretic peptide) in the human placental vasculature

American Journal of Obstetrics and Gynecology, 1995
Our purpose was to compare the actions of atrial natriuretic peptide and brain natriuretic peptide in the human placental vasculature.Isolated placental cotyledons were dually perfused with fetal perfusion pressure used as an index of vascular response.
W. Kossenjans   +4 more
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Dendroaspis natriuretic peptide binds to the natriuretic peptide clearance receptor

Biochemical and Biophysical Research Communications, 2007
Dendroaspis natriuretic peptide (DNP) is a newly-described natriuretic peptide which lowers blood pressure via vasodilation. The natriuretic peptide clearance receptor (NPR-C) removes natriuretic peptides from the circulation, but whether DNP interacts with human NPR-C directly is unknown.
Nabil Elshourbagy   +9 more
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Natriuretic peptide-based screening and collaborative care for heart failure: the STOP-HF randomized trial.

Journal of the American Medical Association (JAMA), 2013
IMPORTANCE Prevention strategies for heart failure are needed. OBJECTIVE To determine the efficacy of a screening program using brain-type natriuretic peptide (BNP) and collaborative care in an at-risk population in reducing newly diagnosed heart ...
M. Ledwidge   +17 more
semanticscholar   +1 more source

Atrial Natriuretic Peptide

Current Opinion in Cardiology, 1986
Publisher Summary The natriuretic peptide system consists of three peptides with similar structures. These peptides cause a wide range of actions in the kidney, the vasculature, the heart, and the central nervous system. Atrial natriuretic peptide (ANP) has subsequently been the subject of extensive investigation.
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The prognostic value of B-type natriuretic peptide in patients with acute coronary syndromes.

New England Journal of Medicine, 2001
BACKGROUND Brain (B-type) natriuretic peptide is a neurohormone synthesized predominantly in ventricular myocardium. Although the circulating level of this neurohormone has been shown to provide independent prognostic information in patients with ...
J. Lemos   +8 more
semanticscholar   +1 more source

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