Results 51 to 60 of about 171,856 (307)

Modified natriuretic peptides and their potential roles in cancer treatment

Biomedical Journal, 2022
The natriuretic peptide family (NPs) is a group of natural endocrine hormones, containing a 17-amino acid ring structure connected by disulfide bonds of two cysteines.
Mengjiao Xu, Xingzhu Liu, Ping Li, Yadong Yang, Wenyuan Zhang, Siyu Zhao, Ying Zeng, Xile Zhou, Ling-hui Zeng, Geng Yang   +9 more
doaj   +1 more source

Oral Bioinspired Peroxisome‐Engineered Probiotics for Modulating Gut Microbiota Homeostasis and Alleviating Cardiac Chemotherapy Toxicity

Advanced Science, EarlyView.
This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang, Xiaowan Fan, Chao Zhang, Shuai Han, Yike Guo, Yuchen Wang, Wei Wang, Junyue Xing, Ying Liu, Wei Jiang, Xiaoying Chen   +10 more
wiley   +1 more source

The predictive value of plasma B-type natriuretic peptide levels on outcome in children with pulmonary hypertension undergoing congenital heart surgery

Revista Brasileira de Anestesiologia, 2014
Background and objectives: In children undergoing congenital heart surgery, plasma brain natriuretic peptide levels may have a role in development of low cardiac output syndrome that is defined as a combination of clinical findings and interventions to ...
Ayse Baysal, Ahmet SŞaşmazel, Ayse Yildirim, Buket Ozyaprak, Narin Gundogus, Tuncer Kocak   +5 more
doaj   +1 more source

Acute effects of insulin on circulating natriuretic peptide levels in humans. [PDF]

PLoS ONE, 2018
The natriuretic peptide hormones play an important role in salt and blood pressure regulation. In observational studies, obesity and insulin resistance have been consistently associated with lower concentrations of natriuretic peptides.
Katherine N Bachmann, Serpil Muge Deger, Aseel Alsouqi, Shi Huang, Meng Xu, Jane F Ferguson, Yan Ru Su, Kevin D Niswender, T Alp Ikizler, Thomas J Wang   +9 more
doaj   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Case report: False-positive B-type natriuretic peptide results with the cyclic amplified fluorescence immunoassay

Journal of International Medical Research
B-type natriuretic peptide, which was initially isolated from porcine brain tissue, has been used in the clinic as an important indicator for the diagnosis, risk stratification, and prognosis of heart failure.
Qian Yin, Fei Wang, Chen Zhang, Yi-bin Pan   +3 more
doaj   +1 more source

Natriuretic Peptides, Diagnostic and Prognostic Biomarkers [PDF]

, 2010
In humans, the natriuretic peptide family consists of three different types of peptides: atrial natriuretic peptide (synonym: atrial natriuretic factor), B-type natriuretic peptide (synonym: brain natriuretic peptide) and C-natriuretic peptide.1 ...
Rutten, J.H.W. (Joost)
core  

Atrial natriuretic factor (ANF) and renin-aldosterone in volume regulation of patients with cirrhosis [PDF]

, 1989
The role of the atrial natriuretic factor and of the main counteracting sodium-retaining principle, the renin-aldosterone system, in acute volume regulation of cirrhosis of the liver has been investigated.
Anderson, Arendt, Arendt, Arendt, Atlas, Ballermann, Bourgorgnie, Campbell, Campbell, Chartier, Cody, Crozier, Cuneo, Epstein, Epstein, Epstein, Epstein, Epstein, Epstein, Epstein, Epstein, Epstein, Gauer, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Goodfriend, Henriksen, Kramer, Laragh, Miki, Needleman, Nicholls, Ogihara, Pendergast, Pugh, Salerno, Sellars, Sherlock, Terblanche, Thibault, Wernze, Wernze, Wilkinson   +46 more
core   +1 more source

Resolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...
Vanina Taliercio, Annabelle Wilcox, Stacey Cole, Josue Flores Daboub, José E. Morales Moreno, Kasey G. Andrews, S. Yukiko Asaki, Thomas A. Pilcher, Martin Tristani‐Firouzi, Mary C. Niu, David Viskochil, Benjamin Hammond   +11 more
wiley   +1 more source

Chronic hyponatremia in a patient with renal salt wasting and without cerebral disease: relationship between RSW, risk of fractures and cognitive impairment [PDF]

, 2018
Renal salt wasting syndrome (RSW) is defined as a renal loss of sodium leading to hyponatremia and a decrease in extracellular fluid volume (ECV). Differentiation of this disorder from the syndrome of inappropriate antidiuretic hormone secretion (SIADH),
Della Corte V., Pecoraro R., Pinto A., Tuttolomondo A.   +3 more
core   +1 more source