Results 71 to 80 of about 966,197 (400)

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

Advanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin, Houxin Fan, Zhenchao Liu, Paolo Donati, Youssef Amin, Yap Wing Fen, Junbo Liang, Pier Paolo Pompa, Sailing He   +8 more
wiley   +1 more source

Doxorubicin Selectively Inhibits Brain versus Atrial Natriuretic Peptide Gene Expression in Cultured Neonatal Rat Myocytes [PDF]

, 1999
Doxorubicin is an antineoplastic agent with significant cardiotoxicity. We examined the effects of this agent on the expression of the natriuretic peptide (NP) genes in cultured neonatal rat atrial myocytes.
Chen, Songcang, Garami, Miklós, Gardner, D. G.   +2 more
core   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source

The use of cardiac biomarkers in veterinary medicine: the equine perspective [PDF]

, 2012
In human medicine, cardiac biomarkers, such as natriuretic peptides and troponins, are routinely used for the diagnosis, prognosis and monitoring of heart diseases.
De Clercq, Dominique, Decloedt, Annelies, Van Der Vekens, Nicky, van Loon, Gunther, Verheyen, Tinne   +4 more
core   +1 more source

The dual endothelin converting enzyme/neutral endopeptidase inhibitor SLV-306 (daglutril), inhibits systemic conversion of big endothelin-1 in humans [PDF]

, 2012
Aims - Inhibition of neutral endopeptidases (NEP) results in a beneficial increase in plasma concentrations of natriuretic peptides such as ANP.
Alison Seed, Ando, Anthony P. Davenport, Battistini, Bayes, Bucchwalder-Csajka, Chen, Christopher Hillier, D'Orleans-Juste, Davenport, Davenport, Davenport, Dhaun, Dickstein, Dive, Emoto, Favrat, Fecteau, Ferro, Fiona Johnston, Flather, Garg, Hand, Hanka J. de Voogd, Hans Essers, Haynes, Haynes, Janet J. Maguire, Jardine, John McMurray, Johnstrom, Kentsch, Ling, Love, Maguire, Maguire, Maguire, McDonagh, McDowell, Naruse, Newby, Northridge, Northridge, O'Connell, Palmer, Plumpton, Rhoda E. Kuc, Richards, Richards, Richards, Rousso, Russell, Russell, Russell, Russell, Schirger, Tabrizchi, Thöne-Reinke, Vachiéry, Van der Meer, Xu, Yanagisawa, Yusuf   +62 more
core   +2 more sources

Natriuretic Peptides and Cardiometabolic Health.

Circulation Journal, 2015
Natriuretic peptides are cardiac-derived hormones with a range of protective functions, including natriuresis, diuresis, vasodilation, lusitropy, lipolysis, weight loss, and improved insulin sensitivity.
D. Gupta, Thomas J. Wang
semanticscholar   +1 more source

Heads and Tails of Natriuretic Peptides: Neuroprotective Role of Brain Natriuretic Peptide [PDF]

Journal of the American Heart Association, 2017
Background Besides the relevant role of brain‐type natriuretic peptide ( BNP ) as biomarker of cardioembolic strokes, new experimental evidences suggest that this peptide may mediate neuroprotective effects.
Antonio Dopico-López, Héctor Fernández-Susavila, Juan M. Doval‐García, José Castillo, Francisco Campos, Susana Arias, Manuel Rodríguez-Yáñez, Paulo Ávila-Gómez, María Santamaría, Ramón Iglesias-Rey, Tomás Sobrino   +10 more
openaire   +4 more sources

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

Advanced Science, EarlyView.
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng, Yansong Wang, Haoyue Huang, Yinglong Ding, Jun Wang, Meili Liu, Kun Song, Lianbo Shao, You Yu, Ziying Yang, Zhenya Shen   +10 more
wiley   +1 more source

Osteocrin ameliorates adriamycin nephropathy via p38 mitogen-activated protein kinase inhibition

Scientific Reports, 2021
Natriuretic peptides exert multiple effects by binding to natriuretic peptide receptors (NPRs). Osteocrin (OSTN) binds with high affinity to NPR-C, a clearance receptor for natriuretic peptides, and inhibits degradation of natriuretic peptides and ...
Takaya Handa, Keita P. Mori, Akira Ishii, Shoko Ohno, Yugo Kanai, Haruko Watanabe-Takano, Akihiro Yasoda, Takashige Kuwabara, Nobuyuki Takahashi, Naoki Mochizuki, Masashi Mukoyama, Motoko Yanagita, Hideki Yokoi   +12 more
doaj   +1 more source

The role of natriuretic peptides in volume assessment and mortality prediction in Haemodialysis patients

BMC Nephrology, 2015
BackgroundMaintaining optimal fluid balance is essential in haemodialysis (HD) patients but clinical evaluation remains problematic. Other technologies such as bioimpedance are emerging as valuable adjuncts.
M. Sivalingam, E. Vilar, S. Mathavakkannan, K. Farrington   +3 more
semanticscholar   +1 more source