Results 271 to 280 of about 8,285,443 (358)
A new paradigm for drug discovery in the treatment of complex diseases: drug discovery and optimization. [PDF]
Yuan Y+8 more
europepmc +1 more source
Summary Data‐driven forecasting of ship motions in waves is investigated through feedforward and recurrent neural networks as well as dynamic mode decomposition. The goal is to predict future ship motion variables based on past data collected on the field, using equation‐free approaches.
Matteo Diez+2 more
wiley +1 more source
Towards Stewardship of Wild Species and Their Domesticated Counterparts: A Case Study in Northern Wild Rice (<i>Zizania palustris</i> L.). [PDF]
McGilp L+7 more
europepmc +1 more source
Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard+7 more
wiley +1 more source
Need for Mechanisms to Monitor Ocean Circulation-Driven Seagrass Population Expansions. [PDF]
Wang Z, Zhou B, Yan W.
europepmc +1 more source
Positively supercharged mGreenLatern protein is self‐assembled electrostatically with negatively charged zinc phthalocyanines to yield bio‐based photoactive materials in aqueous media. The addition of phthalocyanines results in the formation of large complexes fully quenching of the protein fluorescence. The results indicate an energy transfer from the
Sharon Saarinen+10 more
wiley +1 more source
Spatiotemporal Control Over Protein Release from Artificial Cells via a Light‐Activatable Protease
Stimulus‐responsive protein release is essential for intercellular communication. Mimicking this functionality in artificial cells is promising to study the working principles of cellular signaling. Herein, an engineered light‐activatable protease is implemented in a coacervate‐based artificial cell platform to establish user‐defined spatiotemporal ...
Arjan Hazegh Nikroo+4 more
wiley +1 more source
Natures of Naturalism: Reaching Bedrock in Climate Science
openaire +2 more sources