Results 71 to 80 of about 8,784,187 (235)
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
LeCroy, Mary (2013): Type Specimens Of Birds In The American Museum Of Natural History Part 11. Passeriformes: Parulidae, Drepanididae, Vireonidae, Icteridae, Fringillinae, Carduelinae, Estrildidae, And Viduinae.
Mary LeCroy +2 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
The Natural History of Illinois: Illinois State Laboratory of Natural History Bulletin Volume 1 no. 2 [PDF]
This is the second of a series of publications, issued by authority of the State Board of Education of Illinois, and designed especially to elucidate the natural history of this State. The first number was published in December, 1876, as Bulletin No.
Illinois State Laboratory of Natural History
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PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Bulletin of the American Museum of Natural History.
Comprises articles on geology, paleontology, mammalogy, ornithology, entomology and anthropology.Mode of access: Internet.Beginning with v. 23, information on anthropological matter continued in: Anthropological papers of the American Museum of Natural ...
American Museum of Natural History.
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Memòria d’actuació 2001/2011 [PDF]
Resum de la gestió efectuada durant els primers 10 anys del Parc Natural dels Ports, destacant les accions estratègiques i les fites més rellevants en cada un dels àmbits i línies de treball.[es] Gestión efectuada durante los primeros diez años del ...
Parc Natural dels Ports
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