Results 61 to 70 of about 296,182 (247)
There is mixing and second flow in sub-channels of the rod bundle. The flow and heat transfer characteristics in rod bundle are more complex than those in rectangular channel and round pipes.
BI Jingliang;XIE Feng;HUANG Yanping;XU Jianjun;YUAN Dewen;ZAN Yuanfeng
doaj
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla +13 more
wiley +1 more source
A Very High Temperature Reactor (VHTR) is a next generation nuclear reactor system. From a view point of safety characteristic, a passive cooling system should be designed for the VHTR as a best way of a reactor vessel cooling system (VCS).
Kenta FUJIKAMI, Tetsuaki TAKEDA
doaj +1 more source
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation‐associated gene 5 antibody (MDA5 ab) associated dermatomyositis (DM). Methods Thirty patients with MDA5 ab DM were identified in a single center longitudinal cohort of 352 patients with ...
Jenice X Cheah +8 more
wiley +1 more source
Based on the design parameters of the core decay heat removal through natural circulation of the typical high-power sodium-cooled fast reactor, using the system analysis program ERAC, a detailed analysis of the reactor core decay heat removal process ...
ZHOU Zhiwei, XUE Xiuli, LIN Chao, YU Xintai, YANG Yong, YANG Hongyi
doaj +1 more source
Natural circulation of tick-borne severe fever with thrombocytopenia syndrome virus in the city ecosystem, China. [PDF]
Zhang X, Zhao C, Si X, Hu Q, Zheng A.
europepmc +1 more source
Innovating Aircraft Repair Processes: The Role of Digitalization in Sustainability
This research explores how digitalization—by storing detailed non‐destructive testing data in structured DICONDE databases and creating a standard data model of the component—innovates aviation maintenance and repair processes. Coupled with a developed state‐based simulation model, it enables data‐driven, sustainable repair strategies that reduce waste,
Johanna Aigner +3 more
wiley +1 more source

