Results 51 to 60 of about 1,183,079 (307)

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Study on Natural Circulation Heat Transfer Characteristics of Different Liquid Metals Based on Factor Analysis

Frontiers in Energy Research, 2020
The study of the commonness and differences of natural circulation of different liquid metals plays an important role in improving the safety of reactors.
Feng Xiang, Feng Xiang, Feng Xiang, Zhou Tao, Zhou Tao, Zhou Tao, Zhang Jialei, Zhang Jialei, Zhang Jialei, Zhang Boya, Zhang Boya, Zhang Boya, Chen Juan, Chen Juan, Chen Juan   +14 more
doaj   +1 more source

Research on core power maximization method of natural circulation lead-bismuth cooled fast reactor

Frontiers in Energy Research, 2022
To improve the inherent safety and cost-effectiveness of lead-bismuth cooled fast reactors, the SPALLER-100 reactor designed by the University of South China has been selected as the research object to determine the maximum power it can produce.
Yingjie Xiao, Junkang Yang, Pengcheng Zhao, Pengcheng Zhao, Tao Yu, Zijing Liu   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Development and Application of System Analysis Code for Pebble-bed High-temperature Gas-cooled Reactor

Yuanzineng kexue jishu
The safety analysis of pebble-bed high-temperature gas-cooled reactor (PB-HTGR) relies heavily on high-fidelity system-level simulation tools. However, existing analysis codes face significant limitations in modeling the integrated transient response of ...
WU Zhao, HUA Yingjie, WU Pan, SHAN Jianqiang
doaj   +1 more source

CFD Investigation of MHTGR Natural Circulation and Decay Heat Removal in P-LOFC Accident

Frontiers in Energy Research, 2020
One of the key postulated accidents in a high-temperature gas-cooled reactor (HTGR) is the pressurized loss of forced cooling (P-LOFC) of the primary loop, which can be triggered by its primary helium circulator trip or turbine trip.
Chengqi Wang, Xiaodong Sun, Piyush Sabharwall   +2 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Research Progress in Key Thermal-hydraulic Issue of Sodium-cooled Fast Reactor

Yuanzineng kexue jishu
Sodium-cooled fast reactors are considered the preferred reactor type for fourth generation nuclear energy systems due to their high thermal efficiency, high fuel utilization efficiency, inherent safety, and unique advantages of achieving a closed fuel ...
YANG Hongyi1, XUE Xiuli1, , , ZHOU Zhiwei1, LIN Chao1, LI Hongrui2, GAO Xinzhao1, YU Xintai1, MA Xiao1, XIAO Yubai1, LUO Rui2
doaj   +1 more source

Cooling panel wall system with difference types of cooling mediums [PDF]

, 2020
Global warming has caused worldwide average surface temperature to rise about 0.74oC during the past 100 years, which is partly aggravated by air-conditioning that releases chlorofluorocarbons (CFCs) and forming a vicious cycle.
Abd Majid, Masni, Abdul Hamid, Noor Azlina, Abdullah, Siti Radziah, Adnan, Suraya Hani, Ali, Noorwirdawati, Ismail, Noorli, Jamellodin, Zalipah, Mohamad Hashim, Eny Nor Syahira, Salleh, Norhafizah   +8 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source