Results 21 to 30 of about 647,940 (263)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Reevaluating the necessity of static shift correction in magnetotelluric inversion

Frontiers in Earth Science
Magnetotelluric (MT) is a significant electromagnetic exploration method. However, due to uneven distribution of surface charges and other factors, static shift often affects observed data, reducing the accuracy of inversion and interpretation ...
Jingzhong Zeng, Jingzhong Zeng, Xiaobin Chen, Xiaobin Chen, Peijie Wang, Zhongyin Liu, Zhongyin Liu, Juntao Cai, Juntao Cai   +8 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Recognition of the flood- and earthquake-induced deposits in Qionghai Lake: implications for the quantitative analysis of abnormal lacustrine sediments

Frontiers in Earth Science
Lake sediments are an important carrier for recording natural disaster events. The key lies in correctly identifying the causes of abnormal lacustrine sediments.
Yingying Li, Yingying Li, Linlin Li, Linlin Li, Quan Li, Dewen Li, Dewen Li, Yuquan Jiang, Yuquan Jiang   +8 more
doaj   +1 more source

Towards a natural morphology of compounding

Linguistica, 2005
Although compounding is the part of morphology which is closest to syntax, stu­dies in Natural Morphology and Natural Syntax ,as pioneered by Mayerthaler(1981) and Orešnik(2004) have rather avoided the field of composition.This contribution represents a modest tentative towards remedying this lacuna.
openaire   +5 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Spatial distribution patterns and landslide susceptibility analysis from a global–local perspective along the Zhuzhou-Guangzhou section of the Beijing–Guangzhou railway

Frontiers in Earth Science
The Beijing–Guangzhou Railway is a critical transportation corridor in China, with the Zhuzhou–Guangzhou segment particularly susceptible to landslides due to steep terrain and marked climatic variability.
Hanxing Liu, Hanxing Liu, Chong Xu, Chong Xu, Chong Xu, Liye Feng, Liye Feng, Peng Wang, Jingjing Sun, Jingjing Sun, Xuewei Zhang, Xuewei Zhang, Juanling Wang, Qihao Sun, Kang Li   +14 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Escalating risks and impacts of rainfall-induced geohazards

Natural Hazards Research
The increasing impact of climate change has significantly intensified the frequency and severity of rainfall-induced geohazards, posing substantial threats to public safety and economic stability.
Saier Wu, Chong Xu, Junxue Ma, Huiran Gao   +3 more
doaj   +1 more source

Advances on the avoidance zone and buffer zone of active faults

Natural Hazards Research, 2022
Most destructive earthquakes occur along active faults. Abrupt dislocation of active faults in an earthquake and long-term creep during the interseismic period can cause serious damage to buildings and public facilities.
Xiangli He, Chong Xu, Xiwei Xu, Yuchen Yang   +3 more
doaj   +1 more source