Results 91 to 100 of about 1,193,354 (264)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Wyznaczanie gęstości naturalnej gleb = Determination of natural bulk density of soils

open access: yesJournal of Education, Health and Sport, 2015
Wojtasik Mieczysław, Szatten Dawid. Wyznaczanie gęstości naturalnej gleb = Determination of natural bulk density of soils. Journal of Education, Health and Sport. 2015;5(3):218-228. ISSN 2391-8306.
Mieczysław Wojtasik   +1 more
doaj   +2 more sources

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

On products of sets of natural density one

open access: yesMathematical Proceedings of the Cambridge Philosophical Society
Abstract In a previous work, Bettin, Koukoulopoulos, and Sanna prove that if two sets of natural numbers A and B have natural density 1, then their product set
Bettin, Sandro   +2 more
openaire   +2 more sources

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Density of natural numbers and the Lévy group

open access: yesJournal of Number Theory, 1988
Let \(\delta\) be the asymptotic density of natural numbers and \({\mathcal F}\) the collection of subsets of \({\mathbb{N}}\) which admit the density. The triple (\({\mathbb{N}},{\mathcal F},\delta)\) may be regarded as an analogue of a probability space. The Lévy group \({\mathcal G}\) is by definition the subgroup of permutations g on \({\mathbb{N}}\
openaire   +2 more sources

The Nature of Low-Density Star Formation

open access: yes, 2019
Science white paper submitted to the Astro2020 Decadal Survey on Astronomy and ...
Thilker, David   +14 more
openaire   +2 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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