Results 1 to 10 of about 83,045 (262)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Ability of selected basidiomycetous fungi to decay black locust wood

Drewno
Black locust (Robinia pseudoacacia L.) is a non-native tree species wide-spread all over Europe that has already gained some commercial importance. The study assessed ability of selected basidiomycetous fungi (Coniophora puteana, Heterobasidion annosum ...
Andrzej Szczepkowski, Ewa Referowska, Hubert Lachowicz, Szymon Bijak   +3 more
doaj   +1 more source

Editorial on the Special Issue “Application of Petrography, Geochemistry, and Geomechanics to Architectural Heritage”

Applied Sciences, 2023
In historical architecture, which includes many types of monuments and ancient buildings, natural stone was used as the main building material because of its natural beauty, availability and durability [...]
Alba Patrizia Santo
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Resistência Natural de Quatro Espécies Florestais Submetidas a Ensaio com Fungos Apodrecedores

Floresta e Ambiente
Este estudo teve como objetivo avaliar a durabilidade natural das madeiras de Eucalyptus dunnii, Eucalyptus robusta, Eucalyptus tereticornis e Hovenia dulcis submetidas ao ensaio de apodrecimento acelerado em laboratório com os fungos Gloeophyllum ...
Douglas Edson Carvalho, Elio José Santini, Fernando Nunes Gouveia, Márcio Pereira da Rocha   +3 more
doaj   +1 more source

Evaluation of Structural Mortars Made with Mixed Recycled Aggregates with Different Composition

Revista Cubana de Ingeniería, 2013
In the present study are analyzed the mechanical and durability properties of structural mortars made with total replacement of natural aggregates by recycled aggregates.
Iván Martínez Herrera, Elier Pavón de la Fé, Nelson Díaz Brito   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Accelerated Corrosion Analysis of Recycled Aggregate Concrete with Pumice: A Detailed Study on Durability and Performance [PDF]

EPJ Web of Conferences
The study evaluates the durability performance of recycled aggregate concrete (RAC) incorporating pumice as a partial replacement for natural coarse aggregate, with emphasis on accelerated corrosion and acid resistance.
Ramanjaneyulu Ningampalli, Prashanth Ajmeera, Seshagiri Rao M. V, Basha Syed Afzal, Saibab Kothoju, Aravind Kumar Cholker, Uday Kumar A., Vinay Potharaboyena   +7 more
doaj   +1 more source

Durability of self-consolidating concrete containing natural waste perlite powders

Heliyon, 2020
Perlite is a natural glassy volcanic rock used in construction applications requiring improved lightweight, thermal, and acoustic properties. During processing of raw perlite (i.e., cutting and fractioning to different sizes), large amounts of powders ...
Abdulkader El Mir, Salem G. Nehme, Joseph J. Assaad   +2 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source