Results 81 to 90 of about 23,915 (302)

Evil: A Comparative Overview

open access: yes, 2019
The rebirth or revival of academic philosophical interest in the problem of evil has a precise date: September 11, 2001. The terrorist assaults of that day, notably the attacks against the World Trade Center in New York, which claimed the lives of an ...
de Wijze, S., Leezenberg, M., Nys, T.
core   +1 more source

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

open access: yesAdvanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang   +15 more
wiley   +1 more source

Kant on Evil [PDF]

open access: yes
The chapter examines Kant’s thesis about the ‘radical evil in human nature’ developed in his Religion within the Boundaries of Mere Reason. According to this thesis, the human moral condition is corrupt by default and yet by own deed; and this ...
Merritt, Melissa McBay
core   +2 more sources

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

open access: yesAdvanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv   +13 more
wiley   +1 more source

The problem of morality in the Manichaean cosmological and soteriologic system

open access: yesAnales del Seminario de Historia de la Filosofía, 2004
Manicheism is founded in two world originating ontological principles: Good or Light, presented by the sun and Evil or Darkness, personinified in the matter.
Marcos Roberto Nunes Costa
doaj  

Nauka Orygenesa o grzechu

open access: yesWrocławski Przegląd Teologiczny, 2014
Social upheavals in the 3rd century AD, caused by the decline of the paganism, growth of the influence of Gnosticism and strengthening of Christianity, as well as the decline of morals accompanying these social changes, led Orygenes to deep reflection on
Michał Chłopowiec
doaj   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

open access: yesAdvanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun   +10 more
wiley   +1 more source

Problem with the Satan Hypothesis: Natural Evil and Fallen Angel Theodicies

open access: yes, 2017
In contemporary discussions of natural evil, one classically important theodicy—variously called warfare theodicy, fallen angel theodicy, or the Satan hypothesis—is rarely mentioned, let alone defended.
Dunnington, Kent, Kent Dunnington
core   +1 more source

Multiferroic‐Centric Materials and Systems Engineering for Battery Applications: An Insight Into Mechanisms, Strategies, and Characterizations

open access: yesAdvanced Science, EarlyView.
Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su   +13 more
wiley   +1 more source

A Comparative Approach to the Problem of Evil from a Theological and Philosophical Perspective

open access: yesULUM, 2018
The problem of evil is the common problem of both philosophy and theology. Philosophers and kalām scholars have developed a theodicy/defense of divine justice that is in keeping with their understanding of religion, paradigms and methodologies. They have
Metin Özdemir
doaj   +1 more source

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