Results 111 to 120 of about 7,312,015 (303)

Recognition of Masked Faces in the Era of the Pandemic: No Improvement Despite Extensive Natural Exposure. [PDF]

Psychol Sci, 2022
Freud E, Di Giammarino D, Stajduhar A, Rosenbaum RS, Avidan G, Ganel T.   +5 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Evaluating SARS-CoV-2 antibody reactivity to natural exposure and inactivated vaccination with peptide microarrays. [PDF]

Front Immunol, 2023
Zheng P, Ma J, Yang J, Liao B, Cheng ZJ, Xue M, Li S, Fang Y, Lin R, Zhang G, Huang H, Hu F, Ma H, Sun B.   +13 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Occupational exposure to ultraviolet radiation and risk of non-melanoma skin cancer in a multinational European study.

PLoS ONE, 2013
BackgroundStudies suggest that ambient sunlight plays an important role in the pathogenesis of non-melanoma skin cancers (NMSC). However, there is ongoing controversy regarding the relevance of occupational exposure to natural and artificial ultraviolet ...
Simona Surdu, Edward F Fitzgerald, Michael S Bloom, Francis P Boscoe, David O Carpenter, Richard F Haase, Eugen Gurzau, Peter Rudnai, Kvetoslava Koppova, Joëlle Févotte, Giovanni Leonardi, Marie Vahter, Walter Goessler, Rajiv Kumar, Tony Fletcher   +14 more
doaj   +1 more source

Natural Exposure- and Vaccination-Induced Profiles of Ex Vivo Whole Blood Cytokine Responses to Coxiella burnetii. [PDF]

Front Immunol, 2022
Raju Paul S, Scholzen A, Mukhtar G, Wilkinson S, Hobson P, Dzeng RK, Evans J, Robson J, Cobbold R, Graves S, Poznansky MC, Garritsen A, Sluder AE.   +12 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Serological Evidence of Natural Exposure to Tick-Borne Pathogens in Horses, Romania. [PDF]

Microorganisms, 2021
Bogdan AM, Ionita M, Mitrea IL.
europepmc   +1 more source

Construction of natural radiation exposure study network

, 2009
The First Meeting for the International Joint Research on Construction of Natural Radiation Exposure Study Networkconference ...
山澤 弘実, Tokonami, Shinji, Furukawa, Masahide, 孫 全冨, 628351, 628352, Sarata, Kumar Sahoo, 628353, 628354, 628355, Supitcha, Chanyotha, 628356, 628357, 628358, 反町 篤行, 吉永 信治, Miroslaw, JANIK, 628359, Akiba, Suminori, Sakai, Kazuo, 石川 徹夫, Yoshinaga, Shinji, Rakesh, Ramola, 628360, 628361, 628362, 628363, 628364, 628365, 628366, 628367, 628368, 628369, Yamazawa, Hiromi, Sorimachi, Atsuyuki, Kim, Y.J., Sun, Quanfu, 628370, 628371, 628372, 628373, Yonehara, Hidenori, 628374, 秋葉 澄伯, 628375, 628376, Ishikawa, Tetsuo, サフー サラタ クマール, ミロソラフ ヤニック, 米原 英典, 床次 眞司, 酒井 一夫   +51 more
core  

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source