Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Mapping efforts to identify populations at higher risk of lead exposure: HUD perspective [PDF]
HUD-mapping-efforts-populations-high-risk-lead-exposure-Dec-LEPAC-508 ...
core
Environmental Exposure, Biomonitoring and Exposure Assessment
Environmental exposure plays an important role in the development of diseases. However, individuals are exposed to complex mixtures of substances (e.g., chemicals, pollution, and diet) that change throughout a person’s life.
core +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
NATURAL IONIZING IRRADIATION SOURCES IN TYVA REPUBLIC
Радиационная гигиена, 2015 Average annual individual effective doses from natural exposure of the population of Russian Federation are very diverse. At the same time exposure doses inside one territory could also be very different from the average value for this territory. In this
S. A. Daktaalai
doaj
Lead Exposure and Prevention Advisory Committee (LEPAC) : 2021 annual report to U.S. Department of Health and Human Services [PDF]
The objective of the Lead Exposure and Prevention Advisory Committee (LEPAC) is to review research and federal programs and services related to lead poisoning and to identify effective services and best practices for addressing and preventing lead ...
core
The state of natural capital: protecting and improving natural capital for prosperity and wellbeing [PDF]
, 2019 This is the final version. Available from Defra via the link in this record.This is the Natural Capital Committee’s (NCC) third report to government. The report sets out recommendations to achieve government’s vision, ‘to be the first generation to leave
Natural Capital Committee
core
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
The New Natural Resources Economy: Water, Markets, Opportunities
Presented during the Oregon Resource Conservation and Development (RC&D) Conference, Redmond, Oregon, April 23, 2010.This presentation contrasts viewing natural resources as commodities production to viewing them as long term assets with lasting impacts ...
Duncan, Sally +1 more
core +4 more sources
Радиационная гигиена, 2018 The purpose of the study was to estimate the doses to the Voronezh region population from natural sources of ionizing radiation and the technologically altered background in the territory of Voronezh Region.
Yu. I. Stepkin +3 more
doaj +1 more source