Results 71 to 80 of about 7,312,015 (303)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Challenges in Understanding the Risks to Natural and Semi-Natural Vegetation from Ozone Exposure

Italian Journal of Agronomy, 2008
The effects of tropospheric ozone on crops and forests have been studied intensively, but effects on natural and semi- natural plant communities are poorly understood.
J. Neil Cape, Serain Bassin, Jürg Fuhrer, Giacomo Gerosa, Rocio Alonso, Benjamin Gimeno, Ludger Grünhage, Teis N. Mikkelsen, Gina Mills   +8 more
doaj   +1 more source

Exposure classes XA and limiting values for exposure classes for chemical attack from natural soil and groundwater.

, 2019
Exposure classes XA and limiting values for exposure classes for chemical attack from natural soil and groundwater.
Janusz Kozubal (6175769), Dmitri Steshenko (6433169), Marek Wyjadłowski (6433166)   +2 more
core   +1 more source

Natural Hazard Management from a Coevolutionary Perspective: Exposure and Policy Response in the European Alps [PDF]

, 2017
A coevolutionary perspective is adopted to understand the dynamics of exposure to mountain hazards in the European Alps. A spatially explicit, object-based temporal assessment of elements at risk to mountain hazards (river floods, torrential floods, and ...
Sven Fuchs, Andreas Zischg, Margreth Keiler (3345410), Fuchs, Sven, Keiler, Margreth, Veronika Röthlisberger (3345407), Andreas Zischg (3345404), Veronika Röthlisberger, Zischg, Andreas Paul, Margreth Keiler, Sven Fuchs (3345401), Thaler, Thomas, Thomas Thaler (3345413), Thomas Thaler, Röthlisberger, Veronika   +14 more
core   +2 more sources

Concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) in human milk from Ireland: temporal trends and implications for nursing infant exposure

, 2021
Aim: The elucidation of temporal trends in human exposure to polychlorinated biphenyls (PCBs) and 17 polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs) since the previous Irish human milk surveys and to evaluate the impacts of legislative bans and ...
Harrad, Stuart, Keogh, Myra, Cellarius, Claire, Cleere, Kathy, Morrison, John J., Tierney, Julie, Wemken, Nina, Coggins, Marie Ann, Tlustos, Christina, Houlihan, Margarete, O’Riordain, Colman, Noone, Conor, Daly, Sean, Nina Wemken, John J. Morrison, Colman O’Riordain, Christina Tlustos, Sean Daly, Conor Noone, Margarete Houlihan, Stuart Harrad, Myra Keogh, Julie Tierney, Claire Cellarius, Marie Ann Coggins, Kathy Cleere   +25 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Memòria del Parc Natural dels Ports 2024 [PDF]

Gestió efectuada durant el 2024 al Parc Natural dels Ports, destacar les accions estratègiques i les fites més rellevants en cada un dels àmbits i línies de treball.[es] Gestión efectuada durante el 2024 en el Parque Natural de Els Ports, destaca las ...
Parc Natural dels Ports
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Natural light exposure, sleep and depression among day workers and shiftworkers at arctic and equatorial latitudes.

PLoS ONE, 2015
ObjectivesThis study aimed to investigate the relationship between individual natural light exposure, sleep need, and depression at two latitudes, one extreme with a few hours of light per day during winter, and the other with equal hours of light and ...
Elaine Cristina Marqueze, Suleima Vasconcelos, Johanna Garefelt, Debra J Skene, Claudia Roberta Moreno, Arne Lowden   +5 more
doaj   +1 more source

Your brain on nature: A scoping review of the neuroscience of nature exposure

Neuroscience & Biobehavioral Reviews
The relationship between natural environments and human cognition has gathered increasing attention across disciplines, including neuroscience, environmental psychology, and public health. An expanding body of empirical evidence supports the notion that exposure to nature consistently promotes psychological and physiological well-being.
Constanza Baquedano, Antonia Olguí, Luis Sebastian Contreras-Huerta, Fernando E. Rosas, Mar Estarellas   +4 more
openaire   +2 more sources