Results 111 to 120 of about 89,262 (295)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

EPIDEMIOLOGICAL DIFFERENTIATION OF NATURAL FOCI OF HEMORRHAGIC FEVER WITH RENAL SYNDROME OF THE REPUBLIC OF BASHKORTOSTAN

, 2016
Aim. Typization of natural foci of HFRS of the Republic of Bashkortostan and differentiation of their territories by the degree of potential epidemic hazard. Materials and methods.
P. A. Mochalkin, A. P. Mochalkin, L. A. Farvazova, E. G. Stepanov, N. V. Popov   +4 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Designing of the Software Program “Epidemic Potential of Natural Plague Foci in the Territory of the Russian Federation”

, 2014
Designed has been a computer program “Epidemic potential of natural plague foci in the Russian Federation” applied for the automatized evaluation of the epidemic hazard level of natural plague foci in relation to the population residing on the territory ...
V. A. Safronov, E. V. Kouklev, A. A. Lopatin, A. S. Razdorsky   +3 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Impact of the Present-Day Climate Changes on the Natural Plague Foci Condition, Situated in the Territory of the Russian Federation and Other CIS Countries

, 2013
Climate changes determine dynamics of epizootic activity of natural plague foci in the XX and XXI centuries. Obvious shift to continentality in the Northern hemisphere can put an end to inter-epizootic period in lowland steppe and semi-desert natural ...
A. K. Grazhdanov, A. N. Matrosov, T. V. Knyazeva, S. A. Yakovlev, V. V. Kutyrev, T. Z. Ayazbaev, A. I. Udovikov, Yu. M. Fedorov, A. A. Kuznetsov, T. B. Karavaeva, A. A. Sludsky, N. V. Popov, V. E. Bezsmertny, V. P. Popov   +13 more
core   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Principles of Organization and Carrying out of Laboratory Diagnostics in the Mobile Indication Laboratory Used for Epizootiological Surveillance over Particularly Dangerous and Other Natural Foci Infections

, 2012
Determined are optimal structure and basic principles of organization of work in the mobile indication laboratory for carrying-out of epizootiological surveillance over particularly dangerous and other natural foci infections.
E. S. Kazakova, D. A. Shcherbakov, A. V. Toporkov, I. N. Sharova, S. A. Shcherbakova, L. V. Samoylova, V. V. Kutyrev, I. G. Karnaukhov   +7 more
core   +1 more source