Results 121 to 130 of about 89,262 (295)

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Characterization of tularemia foci in the Republic of Kazakhstan from 2000 to 2020

Frontiers in Epidemiology
The wide distribution of tularemia in the territory of Kazakhstan is associated with landscape and geographical characteristics. This is explained by a combination of natural factors: the presence of certain types of rodents—reservoirs and sources ...
U. Izbanova, L. Lukhnova, V. Sadovskaya, Z. Zhumadilova, T. Meka-Mechenko, A. Shevtsov, B. Baitursyn, N. Turebekov, N. Tukhanova   +8 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

NATURAL FOCI OF TULAREMIA IN THE STAVROPOL REGION

Наука. Инновации. Технологии, 2022
Introduction. In recent years, on the territory of the Stavropol region there is a tense situation with many natural focal infections-tularemia, tick-borne encephalitis, leptospirosis and others. The causative agents of these human diseases live in local biocenoses, however, there are also infectious (West Nile fever).
openaire   +1 more source

DETERMINATION OF PHYLOGENETIC RELATIONSHIP OF YERSINIA PESTIS STRAINS FROM NATURAL PLAGUE FOCI OF THE CAUCASUS BY MULTI-LOCUS VNTR-ANALYSIS

, 2017
Aim. Determination of the degree of phylogenetic relationship of Yersinia pestis strains isolated from the territories of natural foci of plague from the Caucasus using VNTR-typing by 25 loci (MLVA25). Materials and methods. 26 strains of Y.
E. B. Zhilchenko, N. S. Serdyuk, A. P. Anisimov, M. E. Platonov, A. N. Kulichenko, O. A. Konyaeva, Yu. M. Evchenko, N. V. Zharinova, V. M. Mezentsev, A. S. Volynkina, I. V. Kuznetsova, E. S. Kotenev   +11 more
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

The Epidemic Situation of Tularemia in Karelia at the Present Time

Эпидемиология и вакцинопрофилактика
Tularemia is a natural focal infection, characterized by the ability to maintain epizootic and epidemic potential for decades and periodically become more active.
T. N. Demidova, L. V. Rubis, A. S. Semikhin, E. A. Gurina, A. V. Amirkhanyan, N. V. Sheenkov, V. V. Gorshenko, Yu. A. Birkovskay   +7 more
doaj   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Concerning the Allocation of Emerging Natural Foci of the Currently Important Infectious Diseases in the West of Kazakhstan

, 2014
Within the period of 2000-2011, in the West of Kazakhstan, identified have been five, previously unknown in the territory, natural foci of dangerous infectious diseases such as hemorrhagic fever with renal syndrome, Astrakhan spotty fever, Crimean ...
L. B. Belonozhkina, A. V. Andryushchenko, T. Z. Ayazbaev, F. G. Bidashko, A. K. Grazhdanov, A. V. Toporkov, A. V. Zakharov, M. V. Pak   +7 more
core   +1 more source