Results 101 to 110 of about 89,262 (295)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
A SOME ECOLOGICAL CHARACTERISTICS OF EBOLA VIRUS IN NATURAL FOCIES
Журнал микробиологии, эпидемиологии и иммунобиологии, 2018 Ebola virus that composed Ebolavirus genus of Filoviridae Family causes severe hemorrhagic fever in humans with high case-fatality rates (up to 90%).
T. E. Sizikova +5 more
doaj +1 more source
Prospects of GIS-Passportization of Natural Plague Foci in the Territory of the Russian Federation
, 2012 Characterized in brief are the results of natural plague foci passportization carried out in the late XX century. Evaluation of the principle of formalized spatial differentiation between enzootic territories is made.
V. P. Toporkov +9 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
CYSTIC ECHINOCOCCOSIS IN THE FAR EASTERN FEDERAL DISTRICT: CURRENT STATE OF THE PROBLEM
Журнал микробиологии, эпидемиологии и иммунобиологии, 2018 Aim. To analyze current epidemiological and epizootological situation on cystic (hydatidiform) echinococcosis in constituent entities of the Far Eastern Federal District (FEFD) of the Russian Federation. Materials and methods. Data of the administrations
A. G. Dragomeretskaya +11 more
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Forest site conditions and other features of Scots pine stands favorable for bark beetles
Наукові праці Лісівничої академії наук України, 2018 The aim of research was to evaluate the dependence of bark beetles foci distribution on forest site conditions as well as on Scots pine stands origin and other characteristics.
Valentyna L. Meshkova +2 more
doaj +1 more source
[A natural opisthorchiasis foci in Kazakhstan].
Meditsinskaia parazitologiia i parazitarnye bolezni, 1989 The structure of many opisthorchiasis foci in Kazakhstan has not been finally determined. Occurrence of opisthorchis in wild animals is not indisputable evidence of the natural character of the focus. The role of humans in the circulation of causative agents is also rather important.
openaire +1 more source
, 2013 Comprehensively studied have been structural elements of ecosystems of Siberian natural plague foci, as well as levels of integration among epizootic process components, and ways of their functional interaction. Application of the complex approach to the
E. A. Vershinin +22 more
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source