Results 21 to 30 of about 84,052 (266)

Epizootic Activity and Epidemic Manifestation of Natural Fod of Tularemia in Voronezh Region

Эпидемиология и вакцинопрофилактика, 2017
Tularemia natural foci were investigated in the 15 districts of the Voronezh region. 1533 small mammals of 11 species were captured in 2011, 2014 and 2015 to identify antigen and/or DNA of tularemia pathogen. In all the studied areas there are continuous
T. V. Mikhaylova, T. N. Demidova, M. I. Kormilitsyna, D. A. Kvasov, A. V. Kozorezov, D. B. Trankvilevsky   +5 more
doaj   +1 more source

The complex genomic diversity of Yersinia pestis on the long‐term plague foci in Qinghai–Tibet plateau

Ecology and Evolution, 2023
Plague is a typical natural focus disease that circulates in different ecology of vectors and reservoir hosts. We conducted genomic population and phylogenetic analyses of the Yersinia pestis collected from the 12 natural plague foci in China with more ...
Junrong Liang, Ran Duan, Shuai Qin, Dongyue Lv, Zhaokai He, Haoran Zhang, Qun Duan, Jinxiao Xi, Hua Chun, Guoming Fu, Xiaojin Zheng, Deming Tang, Weiwei Wu, Haonan Han, Huaiqi Jing, Xin Wang   +15 more
doaj   +1 more source

Tracing the Spatial Circulation of Yersinia pestis of Medieval Biovar in the Eastern Caspian Sea Region in the 20th Century Based on Genome-Wide SNP Analysis

Проблемы особо опасных инфекций, 2022
A comprehensive analysis of the accumulated epidemiological and epizootiological data in combination with results from phylogenetic analysis of Yersinia pestis strains creates the basis for establishing patterns of spatialtemporal distribution of the ...
G. A. Eroshenko, E. G. Oglodin, A. N. Balykova, Ya. M. Krasnov, E. A. Naryshkina, T. Z. Ayazbaev, N. V. Popov, V. V. Kutyrev   +7 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Prognosis of Epizootic Activity of Natural Plague Foci in the Russian Federation for the Year of 2010

Проблемы особо опасных инфекций, 2010
Short-term prognosis of epizootic activity of 11 natural plague foci in Russia for 2010 is substantiated. The analysis of the main plague carries and vectors abundance in natural foci of different types was carried out.
N. V. Popov, V. E. Bezsmertny, V. P. Toporkov, S. M. Ivanova, A. I. Udovikov, A. A. Kuznetsov, T. V. Knyazeva, L. D. Shilova, V. V. Kutyrev   +8 more
doaj   +1 more source

SNP-Profiles of Yersinia pestis Strains of the Medieval Biovar from the Caspian Sea Region Plague Foci

Проблемы особо опасных инфекций, 2023
The SNP-typing method based on the detection of stable genetic markers in the genome, i.e., single nucleotide polymorphisms, is successfully used for genotyping of pathogenic microorganisms and can be applied for SNP-profiling of Yersinia pestis strains ...
A. N. Balykova, L. M. Kukleva, P. A. Goryunova, K. S. Shevchenko, A. V. Kovrizhnikov, Ya. M. Krasnov, N. S. Chervyakova, G. A. Eroshenko, V. V. Kutyrev   +8 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The First Study of Borrelia burgdorferi Sensu Lato Persistence in Small Mammals Captured in the Ixodes persulcatus Distribution Area in Western Siberia

Pathogens
Borrelia burgdorferi sensu lato (s.l.) persistence in reservoir hosts is essential for the maintenance of the spirochaetes in the enzootic cycle. In this study, we investigated the persistence of Siberian B. burgdorferi s.l. strains in naturally infected
Vera Rar, Valeriy Yakimenko, Yana Igolkina, Yuliya Sabitova, Valeria Fedorets, Alfrid Karimov, Gavril Rubtsov, Tamara Epikhina, Nina Tikunova   +8 more
doaj   +1 more source